{"id":"W3192533213","doi":"10.5772/intechopen.99329","title":"Synthetic Gene Circuits for Antimicrobial Resistance and Cancer Research","year":2021,"lang":"en","type":"book-chapter","venue":"IntechOpen eBooks","topic":"Gene Regulatory Network Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Laufer Center for Physical and Quantitative Biology, Stony Brook University; National Defense Science and Engineering Graduate; Government of Canada; National Institutes of Health; University of Alberta; National Institute of General Medical Sciences","keywords":"Synthetic biology; Electronic circuit; Computational biology; Rational design; Gene; Biology; Computer science; Biochemical engineering; Genetics; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001544479,0.000571588,0.0003358638,0.0004464513,0.000206055,0.0008533465,0.0004435067,0.0005926495,0.005608195],"category_scores_gemma":[0.0002841834,0.0002486887,0.0003609686,0.0005014954,0.0009340263,0.001237047,0.0004044109,0.001316085,0.00174647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001000077,"about_ca_system_score_gemma":0.0003380196,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002631307,"about_ca_topic_score_gemma":0.0003329834,"domain_scores_codex":[0.9999081,0.00001434453,0.000003537636,0.00002076635,0.00004741816,0.000005820772],"domain_scores_gemma":[0.9999264,0.00004603353,0.000006326428,0.000007513005,0.000009111767,0.000004647112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000340808,0.00003328053,0.00006476053,0.0004268651,0.00001477063,0.00006577961,0.000120709,0.020912,0.04080854,0.8154429,0.01606957,0.1060068],"study_design_scores_gemma":[0.00001493811,0.00005898927,0.0001595077,0.0001613748,0.00001634315,0.0002849377,0.00004445234,0.03558262,0.02177807,0.3904652,0.5514064,0.00002709533],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.01641123,0.127641,0.5999541,0.005464259,0.002240964,0.0001098687,0.0004580021,0.001730024,0.2459905],"genre_scores_gemma":[0.2217716,0.1561005,0.2761594,0.002239649,0.00080289,0.000537364,0.0007795726,0.0007489924,0.34086],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.005608195,"threshold_uncertainty_score":0.01876128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03543124410998327,"score_gpt":0.30224882925865,"score_spread":0.2668175851486667,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}