{"id":"W3192891376","doi":"10.1002/jcp.21678","title":"Epigenetic control","year":2009,"lang":"en","type":"review","venue":"Journal of Cellular Physiology","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":382,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; U.S. Food and Drug Administration; Canada Research Chairs; National Cancer Institute; CancerCare Manitoba Foundation; Research Manitoba","keywords":"Epigenetics; Biology; Epigenetic regulation of neurogenesis; DNA methylation; Reprogramming; Heterochromatin; Epigenomics; Chromatin; Genetics; Histone; Epigenetics of physical exercise; Euchromatin; Cancer epigenetics; Cell biology; Chromatin remodeling; Histone methyltransferase; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000189507,0.0003800033,0.001335061,0.0001386818,0.00004315119,0.00001348823,0.0005215016,0.0004092195,0.00003077322],"category_scores_gemma":[0.00004669438,0.000299216,0.0008624273,0.00009619627,0.00007696392,0.000001621198,0.00006809261,0.0003170314,0.00002854443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001755523,"about_ca_system_score_gemma":0.0003645929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":3.962327e-7,"about_ca_topic_score_gemma":5.166733e-7,"domain_scores_codex":[0.9981089,0.0002771855,0.0008503337,0.0003055478,0.0001532514,0.0003047814],"domain_scores_gemma":[0.9984968,0.00002368477,0.0009072411,0.0003279977,0.0001191179,0.0001251438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006417352,0.0002014265,0.00000103493,0.00127985,0.000587885,0.00004432791,0.000008094107,0.00003775713,0.2438303,0.00001604744,0.003295236,0.7506338],"study_design_scores_gemma":[0.000471872,0.0008440843,0.00006334588,0.0004246492,0.0003639706,0.0001459726,0.000002989843,8.14277e-7,0.00108859,0.0001211964,0.996181,0.0002915745],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000740809,0.9978636,0.000483542,0.00001543538,0.0004699549,0.0002137507,0.00001114288,0.000002319881,0.0001994598],"genre_scores_gemma":[0.004635265,0.9943184,0.0001983033,0.0001918572,0.0003175844,0.000004989257,0.00007260725,0.00004917426,0.0002117956],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9928857,"threshold_uncertainty_score":0.999946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01402331155617156,"score_gpt":0.2657613166491279,"score_spread":0.2517380050929564,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}