{"id":"W3192891376","doi":"10.1002/jcp.21678","title":"Epigenetic control","year":2009,"lang":"en","type":"review","venue":"Journal of Cellular Physiology","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":382,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; U.S. Food and Drug Administration; Canada Research Chairs; National Cancer Institute; CancerCare Manitoba Foundation; Research Manitoba","keywords":"Epigenetics; Biology; Epigenetic regulation of neurogenesis; DNA methylation; Reprogramming; Heterochromatin; Epigenomics; Chromatin; Genetics; Histone; Epigenetics of physical exercise; Euchromatin; Cancer epigenetics; Cell biology; Chromatin remodeling; Histone methyltransferase; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001353276,0.00103592,0.00085005,0.001491661,0.001846077,0.004732412,0.001975669,0.002170559,0.1390485],"category_scores_gemma":[0.005010187,0.0003526809,0.000891365,0.001480978,0.002706095,0.002551705,0.003668462,0.001816595,0.06908882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001852689,"about_ca_system_score_gemma":0.002550585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002838111,"about_ca_topic_score_gemma":0.002305293,"domain_scores_codex":[0.99765,0.0004177673,0.0001873714,0.000685504,0.000817309,0.0002422118],"domain_scores_gemma":[0.9980836,0.0003632138,0.0002262358,0.0005891487,0.0005463663,0.0001915195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002006198,0.00006892263,0.00248616,0.00163174,0.000114487,0.0008980086,0.001291603,0.00068481,0.01117368,0.2601276,0.2851481,0.4361742],"study_design_scores_gemma":[0.000009739524,0.00001751719,0.000529473,0.0001580969,0.00001536678,0.0003832809,0.00009802166,0.0001038826,0.001341497,0.01061557,0.9867108,0.00001684331],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"review","genre_scores_codex":[0.008367076,0.04520545,0.05066907,0.009573406,0.008904404,0.000534953,0.0120684,0.005549766,0.8591275],"genre_scores_gemma":[0.1819851,0.04557718,0.030985,0.01437748,0.003628052,0.001035678,0.01823695,0.00206074,0.7021137],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.1390485,"threshold_uncertainty_score":0.4651635,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01402331155617156,"score_gpt":0.2657613166491279,"score_spread":0.2517380050929564,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}