{"id":"W3192909378","doi":"10.1002/open.201800017","title":"Front Cover: Early‐Stage Incorporation Strategy for Regioselective Labeling of Peptides using the 2‐Cyanobenzothiazole/1,2‐Aminothiol Bioorthogonal Click Reaction (ChemistryOpen 3/2018)","year":2018,"lang":"en","type":"paratext","venue":"ChemistryOpen","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"TRIUMF","funders":"","keywords":"Bioorthogonal chemistry; Regioselectivity; Cycloaddition; Click chemistry; Combinatorial chemistry; Biocompatible material; Chemistry; Computer science; Flexibility (engineering); Bioconjugation; Nanotechnology; Materials science; Biomedical engineering; Organic chemistry; Mathematics; Engineering; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001407453,0.001100097,0.0004663626,0.0007247512,0.0003138614,0.0004034227,0.0007137365,0.0007703552,0.1155422],"category_scores_gemma":[0.0001547716,0.000465347,0.0003681484,0.0004703689,0.000178372,0.0007880804,0.0004584617,0.0009369213,0.04677521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004704319,"about_ca_system_score_gemma":0.0002576667,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002592072,"about_ca_topic_score_gemma":0.0004208195,"domain_scores_codex":[0.9997953,0.000006255671,0.000007018364,0.00004015929,0.00009756602,0.0000537134],"domain_scores_gemma":[0.9999279,0.00001014754,0.00001124597,0.000007879071,0.00001854911,0.00002424544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003430385,0.0001291699,0.00007081958,0.001055051,0.000015547,0.0004662095,0.0000298982,0.0004387799,0.8103725,0.006205971,0.09400161,0.0868713],"study_design_scores_gemma":[0.00007830028,0.000343496,0.0006377365,0.00004253115,0.00001704571,0.0007716083,0.00001117394,0.002403698,0.6859146,0.0007138813,0.3090327,0.00003320657],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.142124,0.02695405,0.1636638,0.003475915,0.009765775,0.001029597,0.01340905,0.01808155,0.6214963],"genre_scores_gemma":[0.3867142,0.0218782,0.0545831,0.002019525,0.001589621,0.0006299422,0.01732941,0.002121431,0.5131346],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.1155422,"threshold_uncertainty_score":0.3865273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07420258220515566,"score_gpt":0.3261660723648914,"score_spread":0.2519634901597357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}