{"id":"W3193330452","doi":"10.1016/j.neubiorev.2021.08.020","title":"The pilocarpine model of mesial temporal lobe epilepsy: Over one decade later, with more rodent species and new investigative approaches","year":2021,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":103,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"Status epilepticus; Pilocarpine; Neuroscience; Epilepsy; Kainic acid; Rodent; Mesial temporal lobe epilepsy; Optogenetics; Neuroinflammation; Rodent model; Psychology; Epileptogenesis; Temporal lobe; Circadian rhythm; Medicine; Biology; Internal medicine; Glutamate receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001029087,0.001375516,0.001534569,0.001479067,0.0001575554,0.001175831,0.0009354237,0.001002557,0.0016228],"category_scores_gemma":[0.0008584285,0.0001900194,0.0006254531,0.001130649,0.0007793011,0.00134235,0.000617278,0.002764042,0.001161304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008440872,"about_ca_system_score_gemma":0.001627108,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001760602,"about_ca_topic_score_gemma":0.002894052,"domain_scores_codex":[0.9997974,0.000038512,0.00002632418,0.0000380492,0.00007814042,0.00002152009],"domain_scores_gemma":[0.999633,0.0001605809,0.00003799468,0.0000287577,0.0001030224,0.00003663861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005167567,0.0003298081,0.0002102086,0.01168747,0.0001788673,0.0005275967,0.00005920053,0.0004869236,0.02641887,0.009801252,0.02833075,0.9214523],"study_design_scores_gemma":[0.0001312845,0.0006486506,0.001846099,0.002472874,0.000339412,0.002019657,0.00004624024,0.0001535975,0.008453878,0.003475798,0.9803524,0.00006004924],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001106755,0.9929718,0.001045968,0.000949081,0.0005377796,0.0000303748,0.00009388615,0.00004792219,0.00321636],"genre_scores_gemma":[0.002933087,0.9933728,0.00095701,0.0007672093,0.0002636093,0.00002718912,0.0001348842,0.000009654776,0.001534588],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001760602,"threshold_uncertainty_score":0.006124318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.543250964294924,"score_gpt":0.4342753203040144,"score_spread":0.1089756439909096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}