{"id":"W3193443958","doi":"10.1002/iub.2541","title":"Impact of natural mutations on the riboflavin transporter 2 and their relevance to human riboflavin transporter deficiency 2","year":2021,"lang":"en","type":"article","venue":"IUBMB Life","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Sharp Foundation","funders":"","keywords":"Riboflavin; Transporter; Biochemistry; Symporter; Mutant; Chemistry; Flavin adenine dinucleotide; Membrane transport protein; Biology; Gene; Enzyme; Cofactor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001456728,0.0005778667,0.0003201465,0.000195971,0.0001863592,0.0002434324,0.0001933652,0.0008206399,0.001806548],"category_scores_gemma":[0.0003560587,0.00009918535,0.0004518573,0.0001438675,0.0003210467,0.0001165349,0.0002226689,0.0003355927,0.000295089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003098965,"about_ca_system_score_gemma":0.0001720168,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001300414,"about_ca_topic_score_gemma":0.0006696727,"domain_scores_codex":[0.9998525,0.00004354356,0.00002016665,0.00003602151,0.00002922278,0.00001856011],"domain_scores_gemma":[0.9998444,0.00005720165,0.00003480047,0.00001206525,0.00001643767,0.00003505388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002241351,0.0002987195,0.0131951,0.0002122681,0.0002023725,0.0226774,0.0001282743,0.001631837,0.9498608,0.0006522525,0.0005065954,0.008393146],"study_design_scores_gemma":[0.0005946174,0.003663982,0.1245336,0.0001342441,0.0005920408,0.1038406,0.0002915591,0.01337731,0.7330719,0.0009255717,0.01886295,0.0001116543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964736,0.001012332,0.000985463,0.000136916,0.0000419266,0.00002308778,0.0003142298,0.00003751733,0.0009748571],"genre_scores_gemma":[0.9989089,0.0002091223,0.0002971028,0.0000544766,0.0000116236,0.000007895987,0.0002296499,0.00001291658,0.0002682611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001806548,"threshold_uncertainty_score":0.006043553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009745275887097431,"score_gpt":0.268874445862906,"score_spread":0.2591291699758085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}