{"id":"W3193546864","doi":"10.1016/j.nicl.2021.102799","title":"Apolipoprotein E allele 4 effects on Single-Subject Gray Matter Networks in Mild Cognitive Impairment","year":2021,"lang":"en","type":"article","venue":"NeuroImage Clinical","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Janssen Research and Development; National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; Genentech; National Institutes of Health; IXICO; H. Lundbeck A/S; Servier; Eisai; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Seventh Framework Programme; Northern California Institute for Research and Education; Pfizer; Biogen; BioClinica; Fondation Leenaards; F. Hoffmann-La Roche; University of Southern California; Novartis Pharmaceuticals Corporation; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; Foundation for the National Institutes of Health; European Commission; GE Healthcare; Alzheimer's Disease Neuroimaging Initiative; Johnson and Johnson; Meso Scale Diagnostics; Merck; Horizon 2020; Fujirebio Europe; Alzheimer's Association; National Science Foundation","keywords":"Cognition; Apolipoprotein E; Neurodegeneration; Disease; Internal medicine; Psychology; Neuroscience; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006314937,0.0003237135,0.0005203618,0.0001054052,0.0001672097,0.00008817154,0.0002116073,0.0001592238,0.0001539896],"category_scores_gemma":[0.02264412,0.0003106222,0.0002815561,0.0005011512,0.0002734377,0.0001423187,0.0003410154,0.001031611,0.0006427477],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007258365,"about_ca_system_score_gemma":0.00006520285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001455135,"about_ca_topic_score_gemma":0.00007030875,"domain_scores_codex":[0.9951424,0.001741556,0.0006026195,0.001472478,0.0004507551,0.0005902053],"domain_scores_gemma":[0.9711167,0.02804978,0.0001386445,0.0004726131,0.00007435513,0.0001478572],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.009196009,0.02513772,0.4984561,0.0005748062,0.0002680155,0.02618293,0.0007789542,0.002101342,0.1214477,0.0007152187,0.2514602,0.06368103],"study_design_scores_gemma":[0.006342765,0.003622537,0.8440871,0.0003741775,0.00005310409,0.0001324223,0.00005434224,0.001709112,0.1381033,0.0007058223,0.004012775,0.0008025455],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832841,0.00006888266,0.0002320835,0.009877793,0.001490513,0.0007725456,0.0000159759,0.0001192245,0.004138933],"genre_scores_gemma":[0.9370221,0.00004530814,0.00006769146,0.06154679,0.000582105,0.0001102579,0.00000636739,0.00005190952,0.0005674257],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.345631,"threshold_uncertainty_score":0.9999346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07224142425770837,"score_gpt":0.3384611120977973,"score_spread":0.2662196878400889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}