{"id":"W3193583674","doi":"10.2139/ssrn.3506105","title":"Gamma-Aminobutyric Acid Requires GLP-1 Receptor to Effectively Exert Its Pancreatic Function During Streptozotocin Challenge","year":2019,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; St. Michael's Hospital; Brock University; Diabetes Canada; University of Toronto","funders":"","keywords":"Streptozotocin; Glucagon-like peptide 1 receptor; Receptor; Chemistry; Function (biology); Glucagon-like peptide-1; Pancreatic function; Pharmacology; Diabetes mellitus; Cell biology; Endocrinology; Internal medicine; Pancreas; Medicine; Biochemistry; Agonist; Biology; Type 2 diabetes","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001879312,0.0003860987,0.0006446,0.0001489903,0.000156159,0.0002981281,0.0001927515,0.0003178568,0.001408674],"category_scores_gemma":[0.000220463,0.0001255101,0.0003128639,0.000169023,0.000349089,0.0003382766,0.0001830507,0.001574228,0.0003136009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002708371,"about_ca_system_score_gemma":0.0005536088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008492453,"about_ca_topic_score_gemma":0.001667281,"domain_scores_codex":[0.9998068,0.00002433598,0.00002096268,0.00003290808,0.00003609774,0.00007887879],"domain_scores_gemma":[0.9998136,0.00002228238,0.00004303311,0.00002155302,0.00001375509,0.00008588604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008259634,0.0005742735,0.0003681017,0.00005777752,0.00002072423,0.0001669946,0.00003907802,0.00008758032,0.9871538,0.0001136564,0.0001890837,0.002969405],"study_design_scores_gemma":[0.0005412732,0.006969238,0.01299841,0.00001603556,0.00008298996,0.0002773723,0.0001929089,0.00177699,0.9748756,0.0001183232,0.002131037,0.00001967102],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979455,0.000438091,0.0004392042,0.0001282984,0.0001137609,0.00002537634,0.0001632439,0.00003843373,0.0007082052],"genre_scores_gemma":[0.9967847,0.0003774262,0.0004970797,0.00008242352,0.00003165979,0.00004657013,0.0003188728,0.00001195219,0.00184935],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001408674,"threshold_uncertainty_score":0.004712462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007734624136762306,"score_gpt":0.2321188698003852,"score_spread":0.2243842456636228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}