{"id":"W3193714403","doi":"10.1007/s11033-021-06634-0","title":"Identification of TIA1 mRNA targets during human neuronal development","year":2021,"lang":"en","type":"article","venue":"Molecular Biology Reports","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Ontario Ministry of Research and Innovation; University of Toronto; Canada First Research Excellence Fund; Canada Research Chairs; Canada Excellence Research Chairs, Government of Canada; Canada Foundation for Innovation; Ontario Brain Institute; Canadian Institutes of Health Research; Genome Canada","keywords":"Biology; RNA-binding protein; Stress granule; Messenger RNA; Induced pluripotent stem cell; Embryonic stem cell; Translation (biology); Cell biology; Gene knockdown; Molecular biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009304136,0.0001858035,0.0001820504,0.0004953428,0.0001502712,0.0002718126,0.0001364686,0.0001908848,0.0009949043],"category_scores_gemma":[0.0002416541,0.0001074178,0.0001989062,0.0003317964,0.0001201491,0.0001201241,0.0001867063,0.0002124891,0.0007361847],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002595843,"about_ca_system_score_gemma":0.0001659867,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007527382,"about_ca_topic_score_gemma":0.001035396,"domain_scores_codex":[0.9999188,0.000004560598,0.000006238773,0.0000338477,0.00002106871,0.0000154126],"domain_scores_gemma":[0.9998888,0.00002467171,0.00003484136,0.000009253142,0.00002893471,0.00001345593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003158863,0.00001194822,0.01281738,0.0001921491,0.00002885371,0.0002290193,0.0001073926,0.0003770549,0.9758499,0.000113505,0.0004283201,0.009528585],"study_design_scores_gemma":[0.0000137971,0.0001427529,0.200334,0.00003327304,0.0001441499,0.001604875,0.000149513,0.003492882,0.7860156,0.0002347963,0.007813731,0.00002054478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844182,0.003022661,0.005923922,0.00005807972,0.0000210522,0.00002506344,0.004580266,0.0002223056,0.00172861],"genre_scores_gemma":[0.9814469,0.00173549,0.006678402,0.0001055301,0.00001570361,0.00007225052,0.008086641,0.00008788373,0.001771202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009949043,"threshold_uncertainty_score":0.003328264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008315980278774265,"score_gpt":0.2834467720104127,"score_spread":0.2751307917316384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}