{"id":"W3193750231","doi":"10.1158/1055-9965.epi-21-0296","title":"Weight Gain and the Risk of Ovarian Cancer in <i>BRCA1</i> and <i>BRCA2</i> Mutation Carriers","year":2021,"lang":"en","type":"article","venue":"Cancer Epidemiology Biomarkers & Prevention","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juravinski Cancer Centre; Sunnybrook Health Science Centre; Princess Margaret Cancer Centre; Public Health Ontario; Women's College Hospital; University of Toronto","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Women's College Hospital; Shastri Indo-Canadian Institute","keywords":"Ovarian cancer; Medicine; Body mass index; Hazard ratio; Weight gain; Prospective cohort study; Cancer; Oncology; Internal medicine; Gynecology; Risk factor; Anthropometry; Proportional hazards model; BRCA mutation; Weight change; Obstetrics; Obesity; Confidence interval; Weight loss; Body weight","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003271539,0.0002033434,0.0001784965,0.0006027788,0.0002531453,0.0003762656,0.0001856142,0.0003088008,0.001398189],"category_scores_gemma":[0.00128569,0.0002172252,0.0003557006,0.0004417355,0.0001635056,0.0002361054,0.0002507982,0.0004381855,0.0001334961],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001605988,"about_ca_system_score_gemma":0.000148784,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004048846,"about_ca_topic_score_gemma":0.002881224,"domain_scores_codex":[0.9998921,0.00002535608,0.000008750083,0.00002938345,0.00001943506,0.00002504667],"domain_scores_gemma":[0.9991365,0.0001317941,0.0004557728,0.00004912912,0.00005686255,0.0001699554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003055324,0.00002694804,0.9983389,0.000003453397,0.00004013079,0.00004147234,0.00001716341,0.00001834692,0.0003089512,0.00000612948,0.00003545355,0.000857471],"study_design_scores_gemma":[0.00001166629,0.0001438108,0.9993068,0.000003190245,0.00003461319,0.000186286,0.00003531378,0.0001181313,0.00007112753,0.00001538197,0.00007187083,0.000001786726],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995947,0.0001578602,0.00002744395,0.00001824584,0.00000260301,0.000001922434,0.00009559443,0.000001716718,0.00009990379],"genre_scores_gemma":[0.999593,0.00008686302,0.00004008494,0.00001021686,0.000005070017,0.000002422174,0.0001400759,0.000001245493,0.000121016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004048846,"threshold_uncertainty_score":0.008050561,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02148399700426529,"score_gpt":0.3259195976359772,"score_spread":0.3044356006317119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}