{"id":"W3193791362","doi":"10.1093/narcan/zcab034","title":"An emerging picture of FANCJ’s role in G4 resolution to facilitate DNA replication","year":2021,"lang":"en","type":"article","venue":"NAR Cancer","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; National Institute on Aging; National Institutes of Health; Cancer Research Society","keywords":"Helicase; Genome instability; DNA replication; Biology; DNA; Carcinogenesis; DNA repair; Genetics; DNA damage; Eukaryotic DNA replication; Cancer; Cell biology; Computational biology; Gene; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007161312,0.00006608454,0.00007988883,0.00001552467,0.00001926834,0.000004331188,0.00008734238,0.00009554704,0.0000488495],"category_scores_gemma":[0.00003972145,0.00007098106,0.00003128882,0.0001021646,0.00001463246,0.000003192889,0.00003434408,0.00004965863,0.000001871302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002683209,"about_ca_system_score_gemma":0.00006333329,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005044782,"about_ca_topic_score_gemma":0.0001757372,"domain_scores_codex":[0.9993638,0.0000191236,0.0001298008,0.0002947984,0.00007494181,0.0001175713],"domain_scores_gemma":[0.9994254,0.000001643495,0.00003732503,0.0004122285,0.00007845753,0.00004501864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004287067,0.00002508189,0.002507304,0.00001746391,0.000007487711,0.000001052533,0.0002421101,0.0005140734,0.9885348,0.00000548695,0.000901204,0.007201061],"study_design_scores_gemma":[0.000174825,0.00003672473,0.00421892,0.0000181002,0.000004241958,0.000001664789,0.0002747498,0.0001033551,0.9349217,0.00002851575,0.06013561,0.00008155488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969726,0.001222858,0.0002197837,0.0002908756,0.0000492439,0.00005141572,0.00003807493,0.000005958539,0.001149178],"genre_scores_gemma":[0.9982582,0.0001408638,0.000349709,0.0002093447,0.00009935069,0.00002401446,0.0001102948,0.00000865572,0.0007995066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0592344,"threshold_uncertainty_score":0.2894524,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01736719440877786,"score_gpt":0.2899583559995222,"score_spread":0.2725911615907443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}