{"id":"W3194271452","doi":"10.1097/ppo.0000000000000532","title":"Is There a Role for Cellular Therapy in Chronic Lymphocytic Leukemia?","year":2021,"lang":"en","type":"review","venue":"The Cancer Journal","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"AstraZeneca (Canada)","funders":"","keywords":"Chronic lymphocytic leukemia; Chimeric antigen receptor; Medicine; Immunology; Hematopoietic cell; Leukemia; Disease; Transplantation; Hematopoietic stem cell transplantation; Cell therapy; Haematopoiesis; Cancer research; T cell; Cell; Biology; Stem cell; Immune system; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008782746,0.0005459314,0.001253773,0.001125243,0.0002522817,0.001058169,0.0008166331,0.001424667,0.004029715],"category_scores_gemma":[0.0009341211,0.0001613398,0.0004993482,0.001051992,0.0005663473,0.001560503,0.0005808848,0.00276418,0.002455533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000637,"about_ca_system_score_gemma":0.001035055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007238925,"about_ca_topic_score_gemma":0.001311098,"domain_scores_codex":[0.9998017,0.00005399711,0.00002375878,0.00003212044,0.00006700108,0.00002153969],"domain_scores_gemma":[0.9995791,0.0002343261,0.00003892989,0.00001265131,0.00009835996,0.00003660667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001266412,0.00006275853,0.00008797853,0.01072395,0.00007683325,0.0001198212,0.00003492809,0.0002379361,0.00121969,0.005909889,0.03961272,0.9417869],"study_design_scores_gemma":[0.00004247329,0.0001581242,0.0003030881,0.004639477,0.00008618787,0.0005867832,0.00004681701,0.00005959933,0.000298796,0.002525927,0.9912391,0.00001364545],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004423573,0.9985558,0.00005255263,0.0006166143,0.000288338,0.000002309568,0.000008345014,0.000003992014,0.0004278132],"genre_scores_gemma":[0.0004164439,0.998171,0.0001131108,0.0005797804,0.0003009673,0.000005620831,0.00001723158,0.000001277283,0.0003945832],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004029715,"threshold_uncertainty_score":0.01348078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1016404066681494,"score_gpt":0.4152514179338117,"score_spread":0.3136110112656623,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}