{"id":"W3194436560","doi":"10.1089/crispr.2021.0026","title":"Induction and Elimination of Prophages Using CRISPR Interference","year":2021,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Prophage; Lysogenic cycle; Repressor; Biology; SOS response; Genetics; CRISPR interference; Escherichia coli; Lysogen; Bacteriophage; Genome; Cas9; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006043043,0.0009397486,0.0006872113,0.0005424783,0.0003421236,0.0007985176,0.0007322629,0.0008615732,0.002184795],"category_scores_gemma":[0.0005091286,0.0004711603,0.0006834349,0.0003403533,0.0006564629,0.0002572454,0.0008313947,0.001742929,0.0008863203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004415245,"about_ca_system_score_gemma":0.0004213358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006548327,"about_ca_topic_score_gemma":0.001087382,"domain_scores_codex":[0.9989315,0.0001152631,0.0001130272,0.0002775095,0.0003719507,0.0001908896],"domain_scores_gemma":[0.9994569,0.000178113,0.0001310751,0.00009819836,0.00005450862,0.00008121373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003971683,0.00003055843,0.00009268787,0.00006609842,0.000007870305,0.00007726265,0.00002570876,0.00008282065,0.9979956,0.000258846,0.00007759479,0.001245273],"study_design_scores_gemma":[0.00001313759,0.0001383662,0.0007237482,0.000008021451,0.00001569353,0.0001901102,0.00001695605,0.001258973,0.9939148,0.00006410918,0.003643895,0.0000121835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8515436,0.003122173,0.1232451,0.0005415184,0.0004394946,0.001080751,0.002559954,0.002678553,0.01478898],"genre_scores_gemma":[0.9220329,0.001720739,0.05976036,0.0003319604,0.00004061479,0.0006340765,0.002359906,0.0004576505,0.01266181],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002184795,"threshold_uncertainty_score":0.0073089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02457734727006742,"score_gpt":0.2834737434442436,"score_spread":0.2588963961741762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}