{"id":"W3194509158","doi":"10.1371/journal.pgen.1009695","title":"Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations","year":2021,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"National Institute of Justice; National Heart, Lung, and Blood Institute; Vlaamse regering; University of Bristol; University of Washington; University of California Research Initiatives; Pennsylvania State University; Indiana University-Purdue University Indianapolis; National Human Genome Research Institute; Wellcome Trust; National Institute of Dental and Craniofacial Research; Fonds Wetenschappelijk Onderzoek; University of Pennsylvania; Science Foundation Ireland; KU Leuven; March of Dimes Foundation; Medical Research Council; Howard Hughes Medical Institute; U.S. Department of Defense","keywords":"Biology; Craniofacial; Evolutionary biology; Genetics; Population; Genome-wide association study; Genetic architecture; Population stratification; Phenotype; Single-nucleotide polymorphism; Gene; Genotype; Demography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004618395,0.0002546432,0.0002234117,0.001020006,0.0004308358,0.0003170968,0.000187546,0.0003003663,0.002658781],"category_scores_gemma":[0.0009305018,0.0001915275,0.0004043529,0.0008740399,0.00034274,0.0001215616,0.0004751024,0.0002394817,0.0001471384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001441489,"about_ca_system_score_gemma":0.00009637672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00328886,"about_ca_topic_score_gemma":0.005233239,"domain_scores_codex":[0.9997131,0.00006431797,0.00001945625,0.0001178287,0.00003476412,0.00005046297],"domain_scores_gemma":[0.9996938,0.0001058956,0.00009287357,0.00005308785,0.00002610519,0.00002841255],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005026102,0.00004002168,0.9382706,0.00003385065,0.0003173849,0.0007437585,0.0008295877,0.0002257199,0.04724754,0.0002181848,0.0001511656,0.01141962],"study_design_scores_gemma":[0.000005562097,0.00002764772,0.9985188,0.000003245525,0.00004927009,0.0003037975,0.0001515352,0.0002321437,0.0005191755,0.00003914004,0.0001474083,0.000002438503],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995234,0.00006519652,0.0001737647,0.000008510096,7.945437e-7,0.000002151472,0.000103593,0.000004279051,0.0001182174],"genre_scores_gemma":[0.9994603,0.00003440845,0.0003198284,0.000006841484,0.000001352776,0.000003267613,0.0001033001,0.000002526278,0.00006827858],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00328886,"threshold_uncertainty_score":0.008894503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02095099005306532,"score_gpt":0.2886512391781349,"score_spread":0.2677002491250696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}