{"id":"W3194592905","doi":"10.21203/rs.3.rs-55355/v1","title":"CD9 Defines Acute Myeloid Leukemia Stem Cells and is Regulated by Alpha-2-Macroglobulin","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"MD Precision (Canada)","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China; Fundamental Research Funds for the Central Universities; National Science Foundation","keywords":"Myeloid leukemia; Cancer research; Haematopoiesis; Stem cell; Biology; Flow cytometry; Leukemia; Population; Immunology; Medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004775915,0.0001631996,0.00009372516,0.0003320999,0.0001187504,0.0002342743,0.0000681781,0.0001324239,0.001111982],"category_scores_gemma":[0.0000768837,0.00006587325,0.00008268791,0.000183636,0.0001450452,0.00009255979,0.0001365144,0.0001468082,0.0003910985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001680239,"about_ca_system_score_gemma":0.00006840812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002325098,"about_ca_topic_score_gemma":0.0002525202,"domain_scores_codex":[0.9999275,0.000009163304,0.000005435357,0.00002338981,0.00002048334,0.0000139326],"domain_scores_gemma":[0.9999423,0.000007117225,0.00002169597,0.000003071588,0.000009572114,0.00001622013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008397746,0.000005962414,0.001865114,0.00001055036,0.000001938384,0.00003588626,0.000008402621,0.00001940399,0.9970956,0.00005304753,0.00002749016,0.0007926387],"study_design_scores_gemma":[0.00002357223,0.0002672496,0.1928625,0.00001103976,0.00002919271,0.0009171071,0.0001143368,0.001829152,0.7979769,0.0002100192,0.005752522,0.000006392351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975158,0.0005316368,0.001003083,0.00002612703,0.000007918019,0.00001089416,0.0002784734,0.00002099843,0.0006050044],"genre_scores_gemma":[0.9968746,0.0002636138,0.0008738656,0.00002319599,0.000008221876,0.00001734986,0.0006643057,0.000006423418,0.001268369],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001111982,"threshold_uncertainty_score":0.003719985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05013412141770659,"score_gpt":0.3611106161569655,"score_spread":0.3109764947392589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}