{"id":"W3194674665","doi":"10.1089/ars.2021.0152","title":"Oxidative Stress and Mitochondrial Dysfunction Associated with Peripheral Neuropathy in Type 1 Diabetes","year":2021,"lang":"en","type":"review","venue":"Antioxidants and Redox Signaling","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital; University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Oxidative stress; Reactive oxygen species; Mitochondrion; Cell biology; Mitochondrial ROS; Biology; Superoxide; Autophagy; Endocrinology; Biochemistry; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003138399,0.0005395166,0.0006582632,0.0006587357,0.000210745,0.0006840071,0.0003526026,0.0008645189,0.003093963],"category_scores_gemma":[0.0003640935,0.0001253186,0.0003282261,0.0009952314,0.0003619891,0.0007096582,0.0005712474,0.0009820258,0.000507408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004200522,"about_ca_system_score_gemma":0.0004878099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000581331,"about_ca_topic_score_gemma":0.001036902,"domain_scores_codex":[0.9998525,0.00003230897,0.00002397571,0.00002843243,0.00003842379,0.00002441243],"domain_scores_gemma":[0.9997554,0.00005739776,0.00009271956,0.000005435012,0.00005882277,0.00003016135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001252906,0.0001781225,0.01148507,0.03872322,0.0005231806,0.005660318,0.0004769284,0.00124449,0.04430706,0.004864522,0.05215728,0.8391269],"study_design_scores_gemma":[0.00008676539,0.001935673,0.1072106,0.01617187,0.001253939,0.04158599,0.001415217,0.001541042,0.01180476,0.01742501,0.7993692,0.0001999308],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004729064,0.9904172,0.000569356,0.001746056,0.001222614,0.00001020743,0.00007048882,0.00001980887,0.001215284],"genre_scores_gemma":[0.02685997,0.9668409,0.0007358735,0.001103256,0.002270694,0.000014012,0.000129937,0.000007113304,0.002038297],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003093963,"threshold_uncertainty_score":0.01035035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01269729705003699,"score_gpt":0.2573427148571011,"score_spread":0.2446454178070641,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}