{"id":"W3194698214","doi":"10.2217/fon-2021-0087","title":"The Impact of the Host Intestinal Microbiome on Carcinogenesis and the Response to Chemotherapy","year":2021,"lang":"en","type":"review","venue":"Future Oncology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Izaak Walton Killam Health Centre; Dalhousie University","funders":"IWK Health Centre","keywords":"Microbiome; Medicine; Intestinal Microbiome; Colorectal cancer; Dysbiosis; Antibiotics; Cancer; Disease; Fecal bacteriotherapy; Gut microbiome; Probiotic; Inflammatory bowel disease; Immunology; Bioinformatics; Internal medicine; Biology; Microbiology; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003969317,0.0005370984,0.001065815,0.001448285,0.000184349,0.0009044128,0.0005405641,0.0007757221,0.003660919],"category_scores_gemma":[0.0007763917,0.0001685111,0.0004703671,0.001210925,0.0002814168,0.0007496914,0.0005672881,0.001132759,0.001709471],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005321527,"about_ca_system_score_gemma":0.0008352479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000833411,"about_ca_topic_score_gemma":0.001359961,"domain_scores_codex":[0.999836,0.00003805103,0.00002092913,0.00002564489,0.00005973681,0.00001961954],"domain_scores_gemma":[0.9997649,0.0001170088,0.00003396536,0.000006237122,0.00005944478,0.00001847244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009527185,0.00005860026,0.000244226,0.02266176,0.0001195849,0.0001561187,0.00005175273,0.0003279879,0.002160061,0.003793075,0.02295751,0.947374],"study_design_scores_gemma":[0.00001375504,0.0001211755,0.001627658,0.007108284,0.0001591696,0.001135087,0.0000658678,0.0001034334,0.000710011,0.002115665,0.9868204,0.00001943479],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001158525,0.9985771,0.00009185523,0.000264885,0.0001402278,0.000003451386,0.00002343324,0.00000507052,0.000778053],"genre_scores_gemma":[0.000600949,0.9987653,0.00008175016,0.00009849494,0.00009271778,0.00000413044,0.00002352728,9.134912e-7,0.0003321834],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003660919,"threshold_uncertainty_score":0.01224697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01533926363631157,"score_gpt":0.3617463239256036,"score_spread":0.346407060289292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}