{"id":"W3194698214","doi":"10.2217/fon-2021-0087","title":"The Impact of the Host Intestinal Microbiome on Carcinogenesis and the Response to Chemotherapy","year":2021,"lang":"en","type":"review","venue":"Future Oncology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Izaak Walton Killam Health Centre; Dalhousie University","funders":"IWK Health Centre","keywords":"Microbiome; Medicine; Intestinal Microbiome; Colorectal cancer; Dysbiosis; Antibiotics; Cancer; Disease; Fecal bacteriotherapy; Gut microbiome; Probiotic; Inflammatory bowel disease; Immunology; Bioinformatics; Internal medicine; Biology; Microbiology; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009135627,0.0003358903,0.0008987586,0.00004563919,0.0002555309,0.00002428452,0.000601613,0.0004908738,0.00001582653],"category_scores_gemma":[0.0001990331,0.000132509,0.0006329265,0.0002534512,0.0003718111,6.337872e-7,0.0002762469,0.0003578394,0.00000581928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001693693,"about_ca_system_score_gemma":0.001950897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006213313,"about_ca_topic_score_gemma":0.00009897996,"domain_scores_codex":[0.9973319,0.001490326,0.0003916094,0.0003963896,0.00006932952,0.0003204324],"domain_scores_gemma":[0.9982683,0.0003874936,0.0003310695,0.0008265996,0.0001087094,0.00007782163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006008555,0.0002062822,0.0000552928,0.001357532,0.001208576,0.00001734329,0.0006409138,0.000001718575,0.1680857,0.0003373611,0.0731232,0.7489576],"study_design_scores_gemma":[0.0006232625,0.0008479785,0.000990486,0.0004824156,0.0001267352,0.0003776972,0.00006144153,8.101427e-8,0.000437898,0.000002255072,0.9959067,0.0001430544],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01500721,0.9794707,0.000001959397,0.00379861,0.0004827721,0.0009640478,0.00010965,0.000003348816,0.0001617387],"genre_scores_gemma":[0.0009334047,0.9964148,0.00005332385,0.001002886,0.0007264046,0.00006604104,0.00004361746,0.00004219979,0.0007173109],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9227835,"threshold_uncertainty_score":0.5403562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01533926363631157,"score_gpt":0.3617463239256036,"score_spread":0.346407060289292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}