{"id":"W3194699696","doi":"10.1080/16078454.2021.1959984","title":"Refractory acquired thrombotic thrombocytopenic purpura in a patient with sickle cell trait successfully treated with caplacizumab","year":2021,"lang":"en","type":"article","venue":"Hematology","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Health Authority; Saskatchewan Health; University of Saskatchewan","funders":"","keywords":"Sickle cell trait; Medicine; Thrombotic thrombocytopenic purpura; ADAMTS13; Refractory (planetary science); Autoantibody; Immunology; Internal medicine; Pediatrics; Platelet; Disease; Antibody; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003650215,0.001044158,0.001073655,0.001098022,0.001438203,0.001029071,0.0007949747,0.004289399,0.00109287],"category_scores_gemma":[0.002433566,0.0004917812,0.0009344933,0.0006360733,0.000842503,0.0007314086,0.0005839098,0.002479504,0.0005604743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008111955,"about_ca_system_score_gemma":0.0008238476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001230866,"about_ca_topic_score_gemma":0.001521747,"domain_scores_codex":[0.9995197,0.0001021875,0.00005534546,0.00009949184,0.00007354281,0.0001498197],"domain_scores_gemma":[0.9986228,0.0005113605,0.0001688175,0.0001110899,0.00006607281,0.0005199066],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0001042423,0.00006804924,0.004146644,0.00002412554,0.00001577653,0.9921486,0.0001031179,0.000127412,0.000841531,0.0001299905,0.0003960144,0.001894497],"study_design_scores_gemma":[0.0000999266,0.0005779185,0.009255067,0.0000297975,0.00004274996,0.9866925,0.00007326798,0.0008404691,0.0008215863,0.0001938765,0.001354334,0.00001844836],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9620538,0.006375497,0.003179357,0.007487393,0.0007544058,0.0001947964,0.0002865868,0.0002892464,0.01937889],"genre_scores_gemma":[0.9945869,0.0008875466,0.0005643489,0.00160865,0.0008235641,0.00001923299,0.00009518721,0.00002414155,0.00139036],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004289399,"threshold_uncertainty_score":0.005885601,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01099575742150062,"score_gpt":0.2245760727018849,"score_spread":0.2135803152803843,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}