{"id":"W3194857218","doi":"10.1182/bloodadvances.2020003669","title":"Development of immunosuppressive myeloid cells to induce tolerance in solid organ and hematopoietic cell transplant recipients","year":2021,"lang":"en","type":"article","venue":"Blood Advances","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"Immunology; Immune tolerance; Immunosuppression; Myeloid; Myeloid-derived Suppressor Cell; Haematopoiesis; T cell; Transplantation; Microchimerism; Medicine; Immune system; Cancer research; Biology; Stem cell; Internal medicine; Suppressor; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001140787,0.000196239,0.0003986823,0.00008230945,0.00008682071,0.000008328395,0.0002174467,0.0001359967,0.0001689007],"category_scores_gemma":[0.00001639705,0.0001936898,0.00003359818,0.0002239674,0.0001008692,0.000102422,0.0001116703,0.0002177667,0.00005576775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002477797,"about_ca_system_score_gemma":0.0001543441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007550338,"about_ca_topic_score_gemma":0.00005802787,"domain_scores_codex":[0.9986345,0.0000830991,0.0004866034,0.0003889873,0.00005540533,0.0003513641],"domain_scores_gemma":[0.9994162,0.00008695629,0.0001341043,0.0002602979,0.00007805094,0.00002442985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008290019,0.0002769179,0.00229269,0.000118556,0.00004494737,0.00002424875,0.008781916,0.00005053274,0.9844845,0.00001190173,0.00003222236,0.003798702],"study_design_scores_gemma":[0.001484716,0.00005246104,0.004318241,0.0004047982,0.00002520613,0.00004221078,0.0008116473,1.846568e-7,0.9807543,0.00002652589,0.01185606,0.0002237103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9646766,0.03352185,0.00005097519,0.00004533141,0.000838908,0.0001962434,0.00002309592,0.00001577229,0.0006312495],"genre_scores_gemma":[0.9938191,0.001228342,0.003891402,0.0001017958,0.00001015165,0.00004003924,0.00002483813,0.00001870286,0.000865629],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03229351,"threshold_uncertainty_score":0.7898439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006979482396109757,"score_gpt":0.2327630657271686,"score_spread":0.2257835833310588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}