{"id":"W3194931280","doi":"10.2217/fon-2021-0575","title":"Relugolix, An Oral Gonadotropin-Releasing Hormone Antagonist for the Treatment of Prostate Cancer","year":2021,"lang":"en","type":"article","venue":"Future Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"National Institute for Health and Care Research; Cancer Research UK","keywords":"Medicine; Prostate cancer; Testosterone (patch); Gonadotropin-releasing hormone antagonist; Hormone antagonist; Internal medicine; Androgen deprivation therapy; Antagonist; Gonadotropin-releasing hormone; Endocrinology; Androgen; Agonist; Urology; Leuprorelin; Hormone; Cancer; Luteinizing hormone; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007677958,0.0001536455,0.0004159041,0.00004238879,0.0001801951,0.00001349287,0.00006789358,0.0001293474,0.0000975922],"category_scores_gemma":[0.00001645694,0.00008564557,0.0001342811,0.0001795196,0.0001726866,0.00004147667,0.00001735874,0.0001100601,0.000003440468],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005790001,"about_ca_system_score_gemma":0.001175612,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000344755,"about_ca_topic_score_gemma":0.0005225101,"domain_scores_codex":[0.9989114,0.00009309168,0.0002131422,0.0002845379,0.0001485398,0.0003492509],"domain_scores_gemma":[0.9990825,0.0001235661,0.0000843407,0.000312949,0.0002734033,0.0001232586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01096189,0.003572395,0.01132035,0.0002140521,0.001273707,0.0006299177,0.004660785,0.00001879006,0.07273915,0.001347886,0.01039008,0.882871],"study_design_scores_gemma":[0.01057675,0.008630226,0.03584451,0.00003088029,0.0004342716,0.0001025267,0.002133428,0.0001653746,0.01876773,0.0001217169,0.9230739,0.0001186536],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8874903,0.07123756,0.00005509846,0.03745204,0.000975627,0.001774992,0.0002424603,0.00004314779,0.0007287237],"genre_scores_gemma":[0.8139424,0.1609953,0.003808236,0.001149149,0.004093956,0.001455283,0.0008056008,0.0000964361,0.0136536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9126838,"threshold_uncertainty_score":0.3492525,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04279694177607753,"score_gpt":0.3930404528361798,"score_spread":0.3502435110601023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}