{"id":"W3194931280","doi":"10.2217/fon-2021-0575","title":"Relugolix, An Oral Gonadotropin-Releasing Hormone Antagonist for the Treatment of Prostate Cancer","year":2021,"lang":"en","type":"article","venue":"Future Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"National Institute for Health and Care Research; Cancer Research UK","keywords":"Medicine; Prostate cancer; Testosterone (patch); Gonadotropin-releasing hormone antagonist; Hormone antagonist; Internal medicine; Androgen deprivation therapy; Antagonist; Gonadotropin-releasing hormone; Endocrinology; Androgen; Agonist; Urology; Leuprorelin; Hormone; Cancer; Luteinizing hormone; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001639056,0.0002346454,0.0003969489,0.000235911,0.0001429177,0.0002027802,0.0002000648,0.0001939262,0.002865778],"category_scores_gemma":[0.0001418811,0.0000689775,0.0003011631,0.0002346637,0.0001556003,0.0001358221,0.0001667459,0.0007084065,0.000679496],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001860117,"about_ca_system_score_gemma":0.0003462049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006313903,"about_ca_topic_score_gemma":0.002274303,"domain_scores_codex":[0.9999391,0.00001648791,0.000003009759,0.000009677226,0.00001916895,0.00001258739],"domain_scores_gemma":[0.9999447,0.00001051381,0.00001687685,0.000003180888,0.000004911738,0.00001983272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00928504,0.002148092,0.00297194,0.002601867,0.0002327304,0.0009084092,0.00008452102,0.0005312787,0.06179599,0.001307399,0.01881078,0.899322],"study_design_scores_gemma":[0.04017981,0.1646019,0.1085531,0.001251243,0.0009753652,0.0376802,0.0003488065,0.003860128,0.06835929,0.002036326,0.5719173,0.0002366244],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.518113,0.431796,0.005783176,0.003612436,0.001049319,0.0009061066,0.002068735,0.00100515,0.03566615],"genre_scores_gemma":[0.853604,0.1158916,0.00625299,0.00286079,0.0005027144,0.000326252,0.00341141,0.00008674282,0.01706348],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.002865778,"threshold_uncertainty_score":0.009587049,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04279694177607753,"score_gpt":0.3930404528361798,"score_spread":0.3502435110601023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}