{"id":"W3195065451","doi":"10.1021/jacs.1c07240","title":"DNA Dendrons as Agents for Intracellular Delivery","year":2021,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Air Force Office of Scientific Research; Air Force Research Laboratory; National Cancer Institute; Government of Canada","keywords":"Chemistry; Nucleic acid; DNA; Biomolecule; Endocytosis; Conjugated system; Dendrimer; Biophysics; Peptide; Biochemistry; Cell; Nanotechnology; Biology; Organic chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001753251,0.0004783175,0.0001678909,0.0002399365,0.0002176123,0.0003354069,0.000204801,0.000423661,0.0009745336],"category_scores_gemma":[0.000175131,0.0001633206,0.0001429988,0.0001245056,0.000257702,0.0003862635,0.0002665755,0.0004426843,0.0006601586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000730448,"about_ca_system_score_gemma":0.000286454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004508929,"about_ca_topic_score_gemma":0.0007305465,"domain_scores_codex":[0.999897,0.00001860638,0.000008309758,0.00002825329,0.0000318651,0.00001593046],"domain_scores_gemma":[0.9999391,0.00001553548,0.00001414557,0.000005106123,0.00001374298,0.00001232044],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005301721,0.00001329745,0.00004637837,0.0001565954,0.00000571925,0.00007118878,0.00002693107,0.0002406449,0.9906338,0.001037356,0.0002026427,0.00751247],"study_design_scores_gemma":[0.00001275707,0.00006710235,0.00006204917,0.000006670177,0.000008182148,0.00008659343,0.000004621592,0.0005193882,0.9863776,0.0000888067,0.01276154,0.000004720747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7136015,0.07848658,0.1715246,0.001953641,0.001649865,0.0008097781,0.0008928393,0.001600989,0.02948013],"genre_scores_gemma":[0.9047272,0.01432177,0.05688427,0.0004272334,0.00009738505,0.0002977142,0.0004191414,0.00010272,0.02272256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009745336,"threshold_uncertainty_score":0.005299866,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009274059094864482,"score_gpt":0.275886001372696,"score_spread":0.2666119422778315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}