{"id":"W3195065451","doi":"10.1021/jacs.1c07240","title":"DNA Dendrons as Agents for Intracellular Delivery","year":2021,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Air Force Office of Scientific Research; Air Force Research Laboratory; National Cancer Institute; Government of Canada","keywords":"Chemistry; Nucleic acid; DNA; Biomolecule; Endocytosis; Conjugated system; Dendrimer; Biophysics; Peptide; Biochemistry; Cell; Nanotechnology; Biology; Organic chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000135715,0.00009725573,0.0001981533,0.000005671668,0.00006666936,0.00001515963,0.0002192137,0.00006399565,0.000002789078],"category_scores_gemma":[0.0001832979,0.00006620956,0.0007531222,0.0001349425,0.0002103341,0.000002817444,0.0001174086,0.0001375606,3.87722e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003164917,"about_ca_system_score_gemma":0.0001030246,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002475808,"about_ca_topic_score_gemma":6.389684e-7,"domain_scores_codex":[0.9992941,0.00003387711,0.0002225309,0.0001439484,0.0001501537,0.0001553673],"domain_scores_gemma":[0.999101,0.00002395391,0.0003581556,0.0002112558,0.0002419862,0.00006360132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003816152,0.00005466462,0.0001653673,0.000004205883,0.0001778324,0.000002531576,0.00001235202,0.000003235197,0.9742407,0.000003942069,0.02325549,0.002041548],"study_design_scores_gemma":[0.0001763155,0.00008729361,0.00005527236,0.00001325976,0.00009269268,0.0001129554,0.0002139027,0.00002675732,0.9606412,0.0001554612,0.03833627,0.00008860383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962295,0.0002690489,0.0021014,0.001240863,0.00005634057,0.00003823006,0.000008204772,0.000004722245,0.00005167643],"genre_scores_gemma":[0.9753736,0.0004669121,0.02141812,0.002001194,0.0003279277,0.000001197785,0.000009223513,0.0000124043,0.0003894407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02085593,"threshold_uncertainty_score":0.2699947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009274059094864482,"score_gpt":0.275886001372696,"score_spread":0.2666119422778315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}