{"id":"W3195080997","doi":"10.3389/fpain.2021.691740","title":"Impaired Lymphatic Drainage and Interstitial Inflammatory Stasis in Chronic Musculoskeletal and Idiopathic Pain Syndromes: Exploring a Novel Mechanism","year":2021,"lang":"en","type":"article","venue":"Frontiers in Pain Research","topic":"Myofascial pain diagnosis and treatment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Lymphatic system; Medicine; Inflammation; Pathophysiology; Interstitial fluid; Mechanism (biology); Tumor necrosis factor alpha; Cytokine; Immune system; Immunology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005222968,0.000542348,0.000598448,0.0008408177,0.0002845166,0.0007568413,0.000431635,0.001026704,0.002641541],"category_scores_gemma":[0.0004259467,0.000193083,0.0003865879,0.0005284874,0.00207061,0.001859971,0.0008024635,0.0007033467,0.0001996994],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003520501,"about_ca_system_score_gemma":0.000491547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003172467,"about_ca_topic_score_gemma":0.0002620709,"domain_scores_codex":[0.9998641,0.00004632943,0.00001276601,0.00001943311,0.00001768875,0.00003976194],"domain_scores_gemma":[0.9998542,0.00006109258,0.00004308598,0.000007746825,0.00001320121,0.00002063593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.01150409,0.003098911,0.09424813,0.01219058,0.0004683708,0.05292015,0.003812303,0.002652396,0.3026197,0.08192736,0.004372976,0.4301851],"study_design_scores_gemma":[0.002545564,0.0190834,0.4695289,0.002484017,0.001683476,0.1980221,0.01140303,0.02057694,0.08736753,0.1335972,0.05336318,0.0003446171],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6865396,0.2841607,0.01145875,0.008244919,0.0004081466,0.0002427394,0.0001175308,0.00008357714,0.008744034],"genre_scores_gemma":[0.9386606,0.05500569,0.003134147,0.0006204951,0.0007209266,0.0001072507,0.00004696452,0.000004725499,0.001699168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002641541,"threshold_uncertainty_score":0.008836806,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04438203358952601,"score_gpt":0.3069032519080989,"score_spread":0.2625212183185729,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}