{"id":"W3195202932","doi":"10.1503/cmaj.202907","title":"Innovations in cancer immunotherapy: chimeric antigen receptor T-cell therapy (CAR-T)","year":2021,"lang":"en","type":"review","venue":"Canadian Medical Association Journal","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Leukemia & Lymphoma Society of Canada; Canadian Blood Services; Terry Fox Research Institute; University of British Columbia","funders":"","keywords":"Chimeric antigen receptor; Immunotherapy; Cell therapy; Medicine; Cancer immunotherapy; Immunology; Antigen; T cell; CAR T-cell therapy; Cancer; Immune system; Cancer research; Cell; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009892079,0.0008570036,0.001134011,0.002572703,0.0003177946,0.00111283,0.0007754036,0.001440315,0.004767241],"category_scores_gemma":[0.0009933931,0.0002902721,0.0007488086,0.002122567,0.0007621101,0.001575764,0.000718375,0.004559865,0.002824805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001272421,"about_ca_system_score_gemma":0.001221431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001479368,"about_ca_topic_score_gemma":0.002022721,"domain_scores_codex":[0.9996699,0.00006070443,0.00002682417,0.00005760588,0.0001495352,0.00003539619],"domain_scores_gemma":[0.9995281,0.000225867,0.00004059669,0.00001440006,0.0001441141,0.00004697255],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008187208,0.00008068861,0.00009395735,0.008964277,0.00006966467,0.0001393858,0.00003943106,0.0004349207,0.001971201,0.01058968,0.08108569,0.8964492],"study_design_scores_gemma":[0.00002944723,0.00007224427,0.0002340549,0.002128479,0.00004867888,0.0008117353,0.00002074835,0.00009478072,0.0004834206,0.002893819,0.9931695,0.00001309691],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005958617,0.9970837,0.0002499804,0.0008063059,0.0005642063,0.000006473285,0.00001358059,0.00001127686,0.001205016],"genre_scores_gemma":[0.0007660908,0.9966594,0.0002765358,0.0007742675,0.0004601345,0.000009068779,0.00003105277,0.000002858338,0.00102063],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004767241,"threshold_uncertainty_score":0.015948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04552432751642645,"score_gpt":0.3670496104793084,"score_spread":0.321525282962882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}