{"id":"W3195212016","doi":"10.1523/jneurosci.0165-21.2021","title":"Impaired Refinement of Kinematic Variability in Huntington Disease Mice on an Automated Home Cage Forelimb Motor Task","year":2021,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Forelimb; Task (project management); Huntington's disease; Neuroscience; Lever; Medium spiny neuron; Psychology; Macaque; Disease; Medicine; Basal ganglia; Pathology; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004082063,0.001174388,0.0005855014,0.001133068,0.0002113142,0.0004695157,0.000612348,0.0006414439,0.001488937],"category_scores_gemma":[0.0003497194,0.0003370182,0.000502252,0.0002695748,0.0005254073,0.0003073959,0.0004467885,0.001118033,0.0004037509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004620439,"about_ca_system_score_gemma":0.0003302406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001467725,"about_ca_topic_score_gemma":0.003671882,"domain_scores_codex":[0.9995433,0.00005638071,0.00006515568,0.0001513614,0.0001150725,0.00006868305],"domain_scores_gemma":[0.9991867,0.0001073404,0.0003774682,0.00009267883,0.00007263104,0.0001631697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001134723,0.00008885669,0.0004269331,0.00001514437,0.00001038818,0.00003374753,0.00002626692,0.0001038489,0.9978412,0.00003240943,0.00004324253,0.001264476],"study_design_scores_gemma":[0.00007042304,0.001627734,0.03652068,0.00003119882,0.00005842296,0.0003406223,0.00006434468,0.00387331,0.9558674,0.0001010297,0.001408527,0.00003626195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882383,0.0002460558,0.008633626,0.00007856126,0.00002476112,0.0000818434,0.001607034,0.0005339966,0.0005559096],"genre_scores_gemma":[0.9730709,0.0006144737,0.01611263,0.0001520045,0.00001646956,0.0005999405,0.002897406,0.0003621255,0.00617402],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001488937,"threshold_uncertainty_score":0.004980922,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02787406004675704,"score_gpt":0.2978509240644121,"score_spread":0.2699768640176551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}