{"id":"W3195489010","doi":"10.1055/s-0041-1723292","title":"CheckMate 77 T: A phase 3 trial of neoadjuvant nivolumab (NIVO) + chemotherapy (chemo) followed by adjuvant NIVO in resectable early-stage non-small cell lung cancer (NSCLC)","year":2021,"lang":"en","type":"article","venue":"Pneumologie","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Nivolumab; Oncology; Internal medicine; Adjuvant; Stage (stratigraphy); Chemotherapy; Lung cancer; Randomized controlled trial; Neoadjuvant therapy; Cancer; Immunotherapy; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006148765,0.000453341,0.001166151,0.0001996114,0.00008333218,0.0000399042,0.0003386505,0.0003583016,0.001076563],"category_scores_gemma":[0.0001088838,0.000413612,0.0004307028,0.0007839808,0.0001629881,0.000126055,0.0001085665,0.0004967412,0.000009265124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005040794,"about_ca_system_score_gemma":0.001135915,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004107916,"about_ca_topic_score_gemma":0.0004866151,"domain_scores_codex":[0.9967946,0.0001481243,0.0009382939,0.0007988045,0.0004579888,0.000862185],"domain_scores_gemma":[0.9982652,0.0001489386,0.0003835999,0.0008414994,0.0001882272,0.0001725175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.08286582,0.002064928,0.008968213,0.0004045464,0.0002586142,0.0004941485,0.0008545644,0.000007462714,0.8890697,0.000002097931,0.004898605,0.01011133],"study_design_scores_gemma":[0.2228234,0.002041519,0.003913256,0.0005053858,0.000154018,0.00002368349,0.0003886014,0.0004929552,0.7607773,0.00001294604,0.008346101,0.0005208618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9835427,0.009710527,0.000100906,0.001410864,0.000782881,0.00153112,0.0001765785,0.00008999217,0.002654382],"genre_scores_gemma":[0.9813926,0.00589693,0.0003599844,0.000813194,0.0001858835,0.0002646855,0.00009658153,0.00009615164,0.01089401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1399575,"threshold_uncertainty_score":0.9998366,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02237433074829408,"score_gpt":0.3181726230854495,"score_spread":0.2957982923371554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}