{"id":"W3195519228","doi":"10.1016/j.celrep.2021.109584","title":"The macrophage-derived protein PTMA induces filamentation of the human fungal pathogen Candida albicans","year":2021,"lang":"en","type":"article","venue":"Cell Reports","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Canada Foundation for Innovation; Canada Research Chairs; Government of Ontario; Canadian Institutes of Health Research; Ontario Genomics; Genome Canada; Canadian Institute for Advanced Research","keywords":"Filamentation; Candida albicans; Macrophage; Corpus albicans; Biology; Internalization; Immune system; Microbiology; Lysis; Cell biology; Cell; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001121,0.0002360341,0.0001303263,0.0001635411,0.0001255122,0.0001489116,0.0000872571,0.0001571327,0.0009576091],"category_scores_gemma":[0.0001375669,0.00006088517,0.0001866156,0.00008792741,0.0001249423,0.00007211405,0.0001577399,0.0003234618,0.0002055738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001496502,"about_ca_system_score_gemma":0.000139585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002775815,"about_ca_topic_score_gemma":0.0003619148,"domain_scores_codex":[0.9999247,0.00001607282,0.000005097711,0.00001307335,0.00001777214,0.0000233074],"domain_scores_gemma":[0.9999411,0.00001814271,0.00001080237,0.000007775685,0.000006363298,0.00001586094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008299626,0.00001365261,0.0001039644,0.0000128331,0.000001857698,0.00003681385,0.000005550929,0.00001201838,0.9992377,0.00002720833,0.00001554482,0.0004498578],"study_design_scores_gemma":[0.00001053745,0.0002716142,0.00626314,0.000004185214,0.000008542576,0.0002759186,0.00001593142,0.0003727986,0.991698,0.00003187226,0.001045838,0.000001671304],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966239,0.0009202011,0.00127147,0.00007076035,0.0000164565,0.00002510682,0.0001794619,0.00002679377,0.0008657545],"genre_scores_gemma":[0.9967526,0.0004557433,0.001369474,0.00005219868,0.00001064995,0.00002754197,0.0003922244,0.000007692788,0.0009319563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009576091,"threshold_uncertainty_score":0.003203511,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01392905564311507,"score_gpt":0.2646214305739778,"score_spread":0.2506923749308627,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}