{"id":"W3195519228","doi":"10.1016/j.celrep.2021.109584","title":"The macrophage-derived protein PTMA induces filamentation of the human fungal pathogen Candida albicans","year":2021,"lang":"en","type":"article","venue":"Cell Reports","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Canada Foundation for Innovation; Canada Research Chairs; Government of Ontario; Canadian Institutes of Health Research; Ontario Genomics; Genome Canada; Canadian Institute for Advanced Research","keywords":"Filamentation; Candida albicans; Macrophage; Corpus albicans; Biology; Internalization; Immune system; Microbiology; Lysis; Cell biology; Cell; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000347985,0.0001049923,0.0001858628,0.00001192582,0.0002880578,0.00002380579,0.0000691724,0.00006725884,0.0002840453],"category_scores_gemma":[0.0002271595,0.00006021723,0.0001359368,0.0001563086,0.0001671108,0.00003366713,0.00005749975,0.0001791589,0.000003382932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006199347,"about_ca_system_score_gemma":0.0003661501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001224996,"about_ca_topic_score_gemma":0.0003523556,"domain_scores_codex":[0.9986548,0.0001051259,0.0004207851,0.0002632746,0.0003729337,0.0001830137],"domain_scores_gemma":[0.9987553,0.00003937477,0.0002898523,0.0006611668,0.0001896938,0.00006460076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002195786,0.00007621582,0.0793193,0.00007531763,0.00001946166,0.0005269666,0.0003133467,6.615662e-7,0.9184,0.00002284543,0.0003438224,0.0008801457],"study_design_scores_gemma":[0.000159001,0.00003859665,0.3432918,0.00005918687,0.00004076658,0.00005296611,0.0007403492,0.000001168217,0.6539474,0.0001589817,0.001459588,0.00005019053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989027,0.0005868349,0.00001047526,0.0003102326,0.000152446,0.0005014311,0.000006258667,0.00001270614,0.009392587],"genre_scores_gemma":[0.9822297,0.00001855089,0.00005826011,0.00008846248,0.00006354225,0.0000271944,0.00001935233,0.00001289444,0.01748206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2644526,"threshold_uncertainty_score":0.3110096,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01392905564311507,"score_gpt":0.2646214305739778,"score_spread":0.2506923749308627,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}