{"id":"W3195526608","doi":"10.1371/journal.ppat.1009824","title":"pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread","year":2021,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences; Queen's University; University of Bristol; University of Glasgow; Wellcome Trust; University of Pennsylvania; Francis Crick Institute; National Institute for Health and Care Research; Medical Research Council; Royal Society; Wellcome","keywords":"Herpes simplex virus; Signal transducing adaptor protein; Biology; Viral replication; Virus; Virology; Dephosphorylation; Cell biology; Protein phosphatase 1; Phosphatase; Single-stranded binding protein; Phosphorylation; Genetics; DNA-binding protein; Gene; Transcription factor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007739533,0.0001755919,0.0002528443,0.00004875851,0.0001465328,0.00004057858,0.00003399675,0.00009899779,0.0004011949],"category_scores_gemma":[0.0001235334,0.0001523639,0.00008428405,0.0001588876,0.00004696012,0.0001025209,0.00005147908,0.00008817296,0.0001066597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006050402,"about_ca_system_score_gemma":0.00008905704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009896637,"about_ca_topic_score_gemma":0.00003766956,"domain_scores_codex":[0.9988403,0.00004220825,0.0001836729,0.0005058052,0.0001933437,0.0002346802],"domain_scores_gemma":[0.9989493,0.00004271686,0.00006680011,0.0006620596,0.0001015847,0.0001775172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001992336,0.004131361,0.08740237,0.0002339503,0.000985814,0.001171187,0.001243553,3.036108e-7,0.1232636,0.0006308013,0.002711397,0.7780265],"study_design_scores_gemma":[0.001338746,0.0002055457,0.02435513,0.0001153337,0.0004765989,0.0001601901,0.00009050479,0.0002804247,0.8630949,0.0002539922,0.1094153,0.0002133227],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953223,0.00146719,0.0000525977,0.0007359014,0.00004900376,0.0004297244,0.0006907018,0.0001080066,0.001144546],"genre_scores_gemma":[0.995985,0.0004081908,0.001561922,0.0007203866,0.00009707415,0.0001062608,0.0002898332,0.00003316716,0.00079816],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7778131,"threshold_uncertainty_score":0.621322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04440953745942392,"score_gpt":0.2921313048626803,"score_spread":0.2477217674032564,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}