{"id":"W3195539560","doi":"10.1093/nar/gkab682","title":"OUP accepted manuscript","year":2021,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Ontario Brain Institute; Canada's Michael Smith Genome Sciences Centre; University of Toronto; BC Children's Hospital; Simon Fraser University; iCo Therapeutics (Canada); University of British Columbia","funders":"Medical Research Council; Canadian Institutes of Health Research; National Institute of Mental Health; Novo Nordisk Fonden; Wellcome Trust","keywords":"dNaM; Biology; Genetics; DNA methylation; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001754128,0.001255564,0.001334707,0.002167307,0.002067685,0.007728251,0.002429521,0.004149555,0.8315353],"category_scores_gemma":[0.00605836,0.0007524398,0.001080246,0.001579728,0.001268845,0.002261308,0.004855355,0.002829564,0.7770177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001376793,"about_ca_system_score_gemma":0.002427621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002018423,"about_ca_topic_score_gemma":0.002913414,"domain_scores_codex":[0.9980472,0.0003102407,0.0001368446,0.0005658036,0.0006312581,0.0003086054],"domain_scores_gemma":[0.9975364,0.0003481494,0.0001176326,0.0005700142,0.0008075525,0.0006202979],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005129696,0.0002316686,0.001671477,0.001066945,0.00006610999,0.001138502,0.0002458161,0.0002931057,0.004189554,0.01517271,0.7107505,0.2646605],"study_design_scores_gemma":[0.00002467277,0.00002999621,0.0005399531,0.0001021489,0.000004715438,0.0002026246,0.00005372946,0.00008418615,0.0004504171,0.00102871,0.9974718,0.000007086079],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.002767208,0.004464416,0.004219906,0.007781692,0.01973837,0.0003738765,0.01113721,0.003590486,0.9459267],"genre_scores_gemma":[0.007843934,0.001837252,0.001710227,0.001609247,0.001502374,0.0001102112,0.005969761,0.001054759,0.9783623],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.1684647,"threshold_uncertainty_score":0.2402945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06512078966545443,"score_gpt":0.3652881187150548,"score_spread":0.3001673290496004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}