{"id":"W3195599057","doi":"10.1016/j.ydbio.2021.08.004","title":"Protein fucosylation is required for Notch dependent vascular integrity in zebrafish","year":2021,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Japan Society for the Promotion of Science; Natural Sciences and Engineering Research Council of Canada; Memorial University of Newfoundland","keywords":"Fucosylation; Zebrafish; Biology; Cell biology; Mural cell; Notch signaling pathway; Mutant; Phenotype; Fucose; Endothelial stem cell; Signal transduction; Genetics; In vitro; Gene; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001701808,0.000299935,0.0002056828,0.0003061552,0.0003172903,0.0004532291,0.0002200895,0.0003810281,0.001341452],"category_scores_gemma":[0.000223756,0.0003154628,0.0003113476,0.000131934,0.0004033192,0.0002938243,0.0003738213,0.0006851851,0.0004785018],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006666988,"about_ca_system_score_gemma":0.0004169283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002555772,"about_ca_topic_score_gemma":0.004354697,"domain_scores_codex":[0.9998167,0.00001734285,0.0000154268,0.00004363786,0.00006018041,0.0000467457],"domain_scores_gemma":[0.9996821,0.00002978214,0.0001437059,0.00003401019,0.00003904371,0.00007132803],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004203795,0.00000244912,0.0001921391,0.000009839036,0.000002104886,0.00006352925,0.000009445447,0.00003629961,0.9991202,0.0001951829,0.00001666881,0.0003100868],"study_design_scores_gemma":[0.000008659436,0.00003607504,0.01267416,0.000005794055,0.00001362557,0.0002382786,0.00003474481,0.0009675358,0.9839066,0.0001262691,0.001981676,0.000006593365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915245,0.0007557243,0.004639078,0.0001429914,0.00002137164,0.00001460479,0.0003796018,0.0001085219,0.002413529],"genre_scores_gemma":[0.9929494,0.0002486399,0.002194433,0.00006281641,0.000005467943,0.00001323181,0.0003448687,0.00005768927,0.004123665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002555772,"threshold_uncertainty_score":0.005081832,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02486840058549996,"score_gpt":0.3098281128105589,"score_spread":0.2849597122250589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}