{"id":"W3195756613","doi":"10.1002/nbm.4599","title":"Deuterium MRS of early treatment‐induced changes in tumour lactate in vitro","year":2021,"lang":"en","type":"article","venue":"NMR in Biomedicine","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University; Sunnybrook Hospital; University of Toronto; Sunnybrook Health Science Centre","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Extracellular; Apoptosis; Terminal deoxynucleotidyl transferase; Lactate dehydrogenase; Chemistry; Programmed cell death; Haematoxylin; In vitro; Necrosis; Biology; Molecular biology; Biochemistry; Staining; TUNEL assay; Pathology; Medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002214913,0.0003231286,0.0004178273,0.0001760485,0.0001297189,0.0002903083,0.0002408706,0.0003509903,0.0006255938],"category_scores_gemma":[0.0002785202,0.0001884192,0.0001765797,0.0003048074,0.000170522,0.0002194435,0.0002541421,0.0004618693,0.0002030238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002463263,"about_ca_system_score_gemma":0.0002124733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001509252,"about_ca_topic_score_gemma":0.002041263,"domain_scores_codex":[0.9998763,0.00003605302,0.000005816813,0.00001895018,0.00003100128,0.00003194687],"domain_scores_gemma":[0.99989,0.00003308386,0.00002665837,0.00001033537,0.00002672797,0.00001322371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002236753,0.00001473593,0.0001401211,0.0000415389,0.000005431468,0.00004306328,0.00003030311,0.0002497697,0.9984214,0.00002533961,0.00003418686,0.0007704427],"study_design_scores_gemma":[0.00001716414,0.0003504277,0.002773588,0.000005082301,0.00002047187,0.00009365026,0.00004858039,0.002566462,0.9929265,0.00004184933,0.001147926,0.000008222426],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800897,0.003989978,0.01291767,0.0001109349,0.00004845709,0.00004410891,0.0007970609,0.0001005845,0.001901455],"genre_scores_gemma":[0.9869528,0.00288555,0.006660253,0.00007065335,0.00001439875,0.00005472418,0.001017528,0.00004310509,0.002301083],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001509252,"threshold_uncertainty_score":0.003000915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01747464943472744,"score_gpt":0.2801985602920908,"score_spread":0.2627239108573634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}