{"id":"W3195772395","doi":"10.1016/j.neulet.2021.136171","title":"The motor deficit of ALS reflects failure to generate muscle synergies for complex motor tasks, not just muscle strength","year":2021,"lang":"de","type":"review","venue":"Neuroscience Letters","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; University of British Columbia Hospital","funders":"","keywords":"Neuroscience; Motor system; Motor control; Physical medicine and rehabilitation; Psychology; Motor cortex; Primary motor cortex; Motor skill; Cognitive psychology; Medicine; Stimulation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008571196,0.001253619,0.002274587,0.002211122,0.000238333,0.001127376,0.001140433,0.001798148,0.002863559],"category_scores_gemma":[0.001222122,0.0002845616,0.0004612953,0.002327086,0.0008634992,0.001413094,0.000780098,0.002485158,0.003030627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008365645,"about_ca_system_score_gemma":0.001293985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0014003,"about_ca_topic_score_gemma":0.002432665,"domain_scores_codex":[0.9997802,0.00002902514,0.00003494143,0.00004711686,0.00008963594,0.00001902891],"domain_scores_gemma":[0.9993508,0.000321121,0.00009839791,0.00001846622,0.0001558861,0.00005517633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001033059,0.00004151275,0.000193386,0.0122822,0.00012857,0.0002085236,0.00002387066,0.0002008665,0.001538433,0.002924553,0.05022907,0.9321257],"study_design_scores_gemma":[0.00006089649,0.0001124708,0.001991874,0.005573383,0.0002579338,0.001956968,0.00006723728,0.0000811062,0.000487069,0.003840278,0.9855337,0.00003714138],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004274493,0.99884,0.0000612506,0.0004141233,0.0002357125,0.000001667855,0.00001522161,0.000004762104,0.0003844429],"genre_scores_gemma":[0.0003811483,0.998583,0.0001024086,0.000313186,0.000246775,0.000003345144,0.00002869376,0.000001190279,0.000340304],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002863559,"threshold_uncertainty_score":0.009579539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.129257945055935,"score_gpt":0.3716910224521623,"score_spread":0.2424330773962274,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}