{"id":"W3195832088","doi":"10.1038/s41431-021-00952-4","title":"Cascade health service use in family members following genetic testing in children: a scoping literature review","year":2021,"lang":"en","type":"article","venue":"European Journal of Human Genetics","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Clinical Evaluative Sciences; SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Genetic testing; Medicine; Population; Proband; Genetic counseling; Health technology; Family medicine; Health care; Genetics; Environmental health; Biology; Internal medicine; Political science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005862808,0.0001902067,0.000319556,0.0001079637,0.00007267095,0.00009037542,0.00027263,0.00003798056,0.000003455697],"category_scores_gemma":[0.0001626788,0.0001911597,0.0001533104,0.0003597632,0.00001589376,0.000008247193,0.0001568816,0.0002579334,0.000001630194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003080736,"about_ca_system_score_gemma":0.0002946083,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009580392,"about_ca_topic_score_gemma":0.0001110335,"domain_scores_codex":[0.9978952,0.0005576294,0.0008031348,0.0002813551,0.0001689069,0.0002937437],"domain_scores_gemma":[0.9990031,0.00001425786,0.0003405992,0.0002951707,0.0001903945,0.0001565471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00006625838,0.0006615174,0.3940031,0.004317188,0.0004131273,0.01374002,0.001538049,0.008928618,0.5559439,0.000006339514,0.003004708,0.01737718],"study_design_scores_gemma":[0.002714254,0.0007544071,0.9476158,0.04106654,0.000103497,0.002560529,0.0002063359,0.00005253329,0.002710265,0.00001429777,0.001506559,0.0006949812],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7496828,0.2498953,0.00002504929,0.00009109364,0.00008100486,0.0001306522,0.000007106837,0.000002161173,0.00008489568],"genre_scores_gemma":[0.9517412,0.03821886,0.005365166,0.004253136,0.0002735081,0.000001101228,0.00005783179,0.00006010599,0.00002905062],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5536127,"threshold_uncertainty_score":0.7795267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02623953773592645,"score_gpt":0.28079306053791,"score_spread":0.2545535228019835,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}