{"id":"W3195918713","doi":"10.1016/j.jaad.2021.06.592","title":"27454 Efficacy and safety of long-term risankizumab re-treatment following drug withdrawal: IMMhance trial","year":2021,"lang":"en","type":"article","venue":"Journal of the American Academy of Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Medicine; Psoriasis; Drug; Plaque psoriasis; Monoclonal; Dermatology; Internal medicine; Monoclonal antibody; Pharmacology; Antibody; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001286946,0.001111471,0.002503684,0.0002988959,0.0004072246,0.001578295,0.0007470688,0.001508899,0.004574828],"category_scores_gemma":[0.001138116,0.0003655181,0.002499589,0.0002382274,0.0009315822,0.0008729039,0.0003789084,0.003636451,0.001586767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009302098,"about_ca_system_score_gemma":0.0009374789,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006791299,"about_ca_topic_score_gemma":0.001320824,"domain_scores_codex":[0.9993587,0.0002601917,0.00002947783,0.0001003033,0.00007560551,0.0001757023],"domain_scores_gemma":[0.999378,0.0001558628,0.0001137433,0.00006754136,0.00005486133,0.0002300072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8833878,0.005926555,0.005157327,0.0007194477,0.002611732,0.0002705787,0.0001019639,0.0009956006,0.007967832,0.0004635215,0.003989158,0.08840847],"study_design_scores_gemma":[0.7610539,0.1960701,0.02883508,0.0001800786,0.001861618,0.0004608337,0.0001360428,0.001985009,0.003041747,0.0007148691,0.005560264,0.0001005661],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850029,0.00742612,0.0003295904,0.0009371181,0.0004377312,0.0004325774,0.001038928,0.0001119676,0.004282943],"genre_scores_gemma":[0.9893982,0.001935737,0.0002833885,0.001347818,0.0003000392,0.0003354818,0.001562147,0.00002599831,0.004811204],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004574828,"threshold_uncertainty_score":0.01530433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01513750163859811,"score_gpt":0.2884609842801245,"score_spread":0.2733234826415264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}