{"id":"W3195931274","doi":"10.1053/j.gastro.2021.08.016","title":"Co-factors, Microbes, and Immunogenetics in Celiac Disease to Guide Novel Approaches for Diagnosis and Treatment","year":2021,"lang":"en","type":"review","venue":"Gastroenterology","topic":"Celiac Disease Research and Management","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Population Health Research Institute","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Deutsche Forschungsgemeinschaft","keywords":"Immune system; Disease; Genetic predisposition; Immunology; Tissue transglutaminase; Gluten; Medicine; Human leukocyte antigen; Bioinformatics; Biology; Antigen; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007479114,0.0008607518,0.002004591,0.001778649,0.0001857946,0.001171374,0.0008047328,0.001125846,0.004209599],"category_scores_gemma":[0.0009825849,0.000221333,0.0006649588,0.001764997,0.0003833088,0.001186087,0.0007328609,0.002031974,0.001613116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00057571,"about_ca_system_score_gemma":0.001358512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001419933,"about_ca_topic_score_gemma":0.003091644,"domain_scores_codex":[0.999803,0.00004889552,0.00003100265,0.00002509615,0.00007008951,0.00002198692],"domain_scores_gemma":[0.9996062,0.0002308879,0.00005413689,0.000008298749,0.00007627917,0.00002424798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001575485,0.00006577025,0.0002509736,0.03274654,0.0002602224,0.000125691,0.00004232017,0.0002414167,0.001014734,0.003531727,0.0304226,0.9311404],"study_design_scores_gemma":[0.00008580332,0.000146512,0.001605749,0.01944127,0.0005929125,0.0007553858,0.0001085112,0.0001411266,0.0002857311,0.003876441,0.9729322,0.00002828287],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002974596,0.9994728,0.0000383329,0.0001664488,0.000111165,0.000001741224,0.000009744886,0.00000232953,0.0001676134],"genre_scores_gemma":[0.0002662925,0.999099,0.000119901,0.0001629623,0.0001382577,0.000003168997,0.00001915416,5.35682e-7,0.0001906733],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004209599,"threshold_uncertainty_score":0.01408255,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1298247897291882,"score_gpt":0.377490110189554,"score_spread":0.2476653204603659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}