{"id":"W3195988085","doi":"10.1002/art.41955","title":"Association of Increased Serum Lipopolysaccharide, But Not Microbial Dysbiosis, With <scp>Obesity‐Related</scp> Osteoarthritis","year":2021,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; National Center for Chronic Disease Prevention and Health Promotion; National Institute of Diabetes and Digestive and Kidney Diseases; NIH Office of the Director; National Center for Advancing Translational Sciences; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Crohn's and Colitis Foundation; Centers for Disease Control and Prevention; Arthritis Foundation","keywords":"Osteoarthritis; Internal medicine; Body mass index; Medicine; Obesity; Gastroenterology; Dysbiosis; Microbiome; Feces; Gut flora; Immunology; Endocrinology; Biology; Pathology; Microbiology; Bioinformatics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002213142,0.000275595,0.0003117087,0.0004158286,0.0002610693,0.0003938762,0.0001328876,0.000350872,0.003533061],"category_scores_gemma":[0.0006550118,0.0001543453,0.0001810238,0.0002985137,0.0002720407,0.0001504873,0.0002702227,0.0004064034,0.0002560503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001477304,"about_ca_system_score_gemma":0.0002762996,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001105914,"about_ca_topic_score_gemma":0.00116476,"domain_scores_codex":[0.9998206,0.00002891409,0.00002705731,0.00004268403,0.0000458559,0.00003480953],"domain_scores_gemma":[0.9991881,0.0000649659,0.0003624381,0.0000388407,0.00009754462,0.0002480629],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003130263,0.0002569811,0.9598938,0.00008281636,0.00009820273,0.0006989708,0.00005805759,0.00003026345,0.03278114,0.00002215836,0.0001570173,0.002790352],"study_design_scores_gemma":[0.00003516852,0.0007535291,0.9954856,0.000009039132,0.00003754814,0.002132916,0.0001039849,0.0001022009,0.001189345,0.00001294888,0.0001342905,0.00000333543],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994764,0.0001598389,0.00006016411,0.00002676598,0.000003927508,0.000006323025,0.00008521826,0.000002387886,0.000179046],"genre_scores_gemma":[0.9995999,0.00005305483,0.0000711465,0.00001960359,0.000007007363,0.000005140934,0.0001071205,8.79917e-7,0.0001362315],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003533061,"threshold_uncertainty_score":0.0118193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003213670525445912,"score_gpt":0.1967578757477434,"score_spread":0.1935442052222975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}