{"id":"W3196014795","doi":"10.2174/1567201818666210820101549","title":"Release Kinetics of Hydroxypropyl Methylcellulose Governing DrugRelease and Hydrodynamic Changes of Matrix Tablet","year":2021,"lang":"en","type":"article","venue":"Current Drug Delivery","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Kinetics; Chemistry; Matrix (chemical analysis); Drug; Liberation; Chromatography; Chemical engineering; Pharmacology; Biochemistry; Medicine; In vitro; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001959835,0.0002306881,0.0001429006,0.0001619996,0.00009285983,0.0002132469,0.000128099,0.0002058766,0.001034335],"category_scores_gemma":[0.0004168562,0.0001003999,0.0002149166,0.0001469789,0.0001290866,0.0002869747,0.0000677912,0.0003221996,0.0002395763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003181485,"about_ca_system_score_gemma":0.000192914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00105688,"about_ca_topic_score_gemma":0.0004919556,"domain_scores_codex":[0.9998282,0.00001327867,0.00001300307,0.0000443413,0.00007627443,0.00002488256],"domain_scores_gemma":[0.9998248,0.00005487424,0.00006407274,0.000009964201,0.00003366027,0.00001265879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001847181,0.00002493081,0.0008586923,0.00008423769,0.000009657193,0.00006888281,0.00004820936,0.0003746345,0.993722,0.00009452852,0.0000526758,0.00447679],"study_design_scores_gemma":[0.00001341827,0.0004070239,0.00784848,0.00000697082,0.0000178016,0.0001269712,0.00001723334,0.006175893,0.984346,0.00003874253,0.0009918627,0.000009690825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898388,0.002900477,0.005070558,0.00005123891,0.0000162063,0.00005682094,0.0004248011,0.00006778038,0.001573245],"genre_scores_gemma":[0.9961863,0.0008741877,0.001948923,0.00001327944,0.000008008058,0.00002949965,0.0002019395,0.00001211525,0.0007257389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00105688,"threshold_uncertainty_score":0.003460228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05898786184541745,"score_gpt":0.3759110717001415,"score_spread":0.3169232098547241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}