{"id":"W3196014795","doi":"10.2174/1567201818666210820101549","title":"Release Kinetics of Hydroxypropyl Methylcellulose Governing DrugRelease and Hydrodynamic Changes of Matrix Tablet","year":2021,"lang":"en","type":"article","venue":"Current Drug Delivery","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Kinetics; Chemistry; Matrix (chemical analysis); Drug; Liberation; Chromatography; Chemical engineering; Pharmacology; Biochemistry; Medicine; In vitro; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000684169,0.0003426084,0.000689222,0.0001726693,0.0001118681,0.00001861296,0.0002741836,0.0002378537,0.0003382986],"category_scores_gemma":[0.0001855337,0.0003641908,0.0001818845,0.0004102927,0.0003759919,0.0001437045,0.0003155333,0.0006797347,0.00006204889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007735685,"about_ca_system_score_gemma":0.0001549528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001024594,"about_ca_topic_score_gemma":0.00007943039,"domain_scores_codex":[0.997074,0.000784366,0.0007338555,0.0005249373,0.0003680278,0.0005148122],"domain_scores_gemma":[0.9977654,0.000596238,0.0005309875,0.0004140983,0.0003595304,0.0003337132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001322931,0.004365971,0.01990749,0.007074746,0.001106017,0.0004191961,0.006437185,0.00510227,0.8219923,0.001540014,0.02325987,0.107472],"study_design_scores_gemma":[0.005157578,0.0002972999,0.001036278,0.0006180796,0.001419209,0.0001070547,0.002037755,0.08518811,0.5959767,0.0004360553,0.3065215,0.00120436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9357008,0.06005308,0.00009845538,0.0002684356,0.001795101,0.0003239245,0.0005932981,0.00005580114,0.001111123],"genre_scores_gemma":[0.9895735,0.008784204,0.0001214691,0.0001327777,0.0002138753,0.00001844261,0.0001540672,0.00003562963,0.0009659973],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2832616,"threshold_uncertainty_score":0.999881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05898786184541745,"score_gpt":0.3759110717001415,"score_spread":0.3169232098547241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}