{"id":"W3196024952","doi":"10.3390/genes12091310","title":"Polymerase θ Coordinates Multiple Intrinsic Enzymatic Activities during DNA Repair","year":2021,"lang":"en","type":"review","venue":"Genes","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Telesta Therapeutics (Canada)","funders":"National Cancer Institute; Gray Foundation","keywords":"Polymerase; DNA polymerase; Biology; DNA polymerase beta; DNA clamp; DNA repair; Base excision repair; DNA; Homologous recombination; Genetics; Molecular biology; Gene; Cell biology; Polymerase chain reaction; Reverse transcriptase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003577372,0.001044228,0.0008330168,0.001603634,0.0002240724,0.001128763,0.0008574753,0.0008767307,0.002069881],"category_scores_gemma":[0.0002853209,0.0003650062,0.0003124597,0.001760587,0.0006715664,0.001345655,0.0007203316,0.001377151,0.00364595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008825395,"about_ca_system_score_gemma":0.0008870249,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008858142,"about_ca_topic_score_gemma":0.000905287,"domain_scores_codex":[0.9998237,0.00002148305,0.00002013548,0.00004849812,0.0000641751,0.00002198018],"domain_scores_gemma":[0.9998963,0.00003544522,0.00001977078,0.000004606822,0.0000315679,0.00001223426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001010378,0.00005057084,0.0002335947,0.01022633,0.00005099057,0.0001959583,0.00007964884,0.0006897472,0.01327849,0.01108366,0.01236565,0.9516442],"study_design_scores_gemma":[0.000009796971,0.00006579825,0.0005649255,0.001015363,0.00003465182,0.0008971363,0.0000410644,0.00008965602,0.004455261,0.0020858,0.9907225,0.00001806162],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003072779,0.9957671,0.000810716,0.0001594038,0.0001764557,0.000007552978,0.00003301369,0.00002815775,0.002710247],"genre_scores_gemma":[0.001461259,0.9964002,0.0004401573,0.00007281703,0.00009670167,0.00001077924,0.00006111888,0.000003605744,0.001453324],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002069881,"threshold_uncertainty_score":0.00692445,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01827298848219506,"score_gpt":0.2733742779631095,"score_spread":0.2551012894809145,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}