{"id":"W3196234584","doi":"10.1101/2021.08.25.457678","title":"Hematopoiesis at single cell resolution spanning human development and maturation","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Haematopoiesis; Progenitor cell; Biology; Cell biology; Stem cell; Immunology; Cell; Regeneration (biology); Cell fate determination; Progenitor; RNA; Gene; Genetics; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002834231,0.0001528072,0.0002543806,0.0002964657,0.0001862455,0.0003506991,0.0001365636,0.0002827688,0.001349462],"category_scores_gemma":[0.000287842,0.0001876374,0.0001527924,0.0002850392,0.0002038751,0.0001531538,0.0002890688,0.0003009111,0.0006787989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001758606,"about_ca_system_score_gemma":0.0001945245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009510484,"about_ca_topic_score_gemma":0.00127705,"domain_scores_codex":[0.9998838,0.00001218027,0.000005942161,0.00004900834,0.00003722059,0.00001190486],"domain_scores_gemma":[0.9998715,0.00004154757,0.00001655528,0.00002364818,0.00003287103,0.00001383325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00008401577,0.000008590579,0.003761772,0.00008975276,0.00002039618,0.00006945962,0.0001003593,0.001075801,0.9765372,0.0005551354,0.0008008035,0.01689675],"study_design_scores_gemma":[0.00001467359,0.0001147332,0.0981219,0.00004624741,0.00007995043,0.0009070157,0.000216585,0.01739187,0.850307,0.002079761,0.03068662,0.00003366538],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8690059,0.004001681,0.1057082,0.0003321296,0.00009845491,0.0000665543,0.01150526,0.001409252,0.007872559],"genre_scores_gemma":[0.9365122,0.002005479,0.04849141,0.0002617666,0.00004977731,0.0001091184,0.007980005,0.0003622497,0.004227808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001349462,"threshold_uncertainty_score":0.004514337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01676842092133472,"score_gpt":0.2050231539570486,"score_spread":0.1882547330357139,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}