{"id":"W3196289881","doi":"10.3389/fgene.2021.737433","title":"Established and Emerging Regulatory Roles of Eukaryotic Translation Initiation Factor 5B (eIF5B)","year":2021,"lang":"en","type":"review","venue":"Frontiers in Genetics","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Lethbridge","funders":"Natural Sciences and Engineering Research Council of Canada; University of Lethbridge","keywords":"Eukaryotic initiation factor; Eukaryotic translation; Cell biology; Translation (biology); Biology; Initiation factor; eIF2; Cancer research; Messenger RNA; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004443503,0.0007255165,0.000693351,0.001248093,0.0002357831,0.0007576712,0.0005038391,0.0007554571,0.002100313],"category_scores_gemma":[0.0004401995,0.0001853125,0.0002917715,0.001390078,0.0004470283,0.001119414,0.0005809501,0.001497539,0.001586559],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005945885,"about_ca_system_score_gemma":0.001088288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006095164,"about_ca_topic_score_gemma":0.000787305,"domain_scores_codex":[0.9998786,0.00001523453,0.00001723431,0.00002418144,0.00004680092,0.0000177989],"domain_scores_gemma":[0.9998499,0.00006399252,0.0000219236,0.000005047567,0.00004188643,0.00001725041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008390295,0.00003046116,0.0002265723,0.01377585,0.00004557228,0.0003201743,0.00008978547,0.0003125005,0.006931632,0.008750249,0.01372287,0.9557105],"study_design_scores_gemma":[0.000007655138,0.00005426667,0.0007731172,0.001270103,0.00005921006,0.001042992,0.00005030414,0.00007302344,0.001456574,0.002259423,0.992939,0.00001444463],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002212241,0.9976863,0.0002584905,0.0002545238,0.0002279211,0.00000286347,0.00002204261,0.00001084104,0.001315864],"genre_scores_gemma":[0.001345802,0.9975922,0.0002936829,0.000122401,0.000109945,0.000003542215,0.00003933933,0.000001573123,0.000491533],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002100313,"threshold_uncertainty_score":0.007026255,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02447078728231282,"score_gpt":0.2725838602849875,"score_spread":0.2481130730026747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}