{"id":"W3196339311","doi":"10.3177/jnsv.67.249","title":"Newly Developed Highly Bioavailable Curcumin Formulation, curcuRouge<sup>TM</sup>, Reduces Neutrophil/Lymphocyte Ratio in the Elderly: A Double-Blind, Placebo-Controlled Clinical Trial","year":2021,"lang":"en","type":"article","venue":"Journal of Nutritional Science and Vitaminology","topic":"Curcumin's Biomedical Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Debiopharm Group (Canada)","funders":"","keywords":"Medicine; Placebo; Lymphocyte; White blood cell; Internal medicine; Curcumin; Neutrophil to lymphocyte ratio; Absolute neutrophil count; Gastroenterology; Immunology; Clinical trial; Placebo-controlled study; Pharmacology; Double blind; Pathology; Toxicity; Neutropenia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009349925,0.001109464,0.002155145,0.0003489737,0.0003589087,0.0004419315,0.0006268459,0.001346696,0.00253253],"category_scores_gemma":[0.0004740877,0.0003831949,0.0009207294,0.0002585773,0.0006203174,0.000654799,0.0002532018,0.001352479,0.0003768494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002790832,"about_ca_system_score_gemma":0.0006284521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006058655,"about_ca_topic_score_gemma":0.0016231,"domain_scores_codex":[0.9998148,0.00005486349,0.00002492495,0.00005303265,0.00002307233,0.0000292923],"domain_scores_gemma":[0.9997581,0.00003968707,0.00006141568,0.00001794574,0.00002917127,0.00009374183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8421607,0.03874912,0.0004826972,0.003282875,0.001395578,0.00009506123,0.00007817376,0.0002294525,0.07553164,0.00008927452,0.001098239,0.03680714],"study_design_scores_gemma":[0.5190325,0.4599226,0.005266434,0.0001148434,0.001516727,0.00008930386,0.00005134509,0.0005566661,0.01060422,0.0000823022,0.002720568,0.00004254722],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825699,0.0119359,0.0009273486,0.0004241915,0.0004273322,0.002156953,0.0006888535,0.000139759,0.0007299046],"genre_scores_gemma":[0.9796173,0.009690218,0.002490047,0.0006953402,0.0004002046,0.002863475,0.0006494301,0.00002191829,0.003572017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00253253,"threshold_uncertainty_score":0.008472204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05601092681220768,"score_gpt":0.3451332955919999,"score_spread":0.2891223687797922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}