{"id":"W3196339311","doi":"10.3177/jnsv.67.249","title":"Newly Developed Highly Bioavailable Curcumin Formulation, curcuRouge<sup>TM</sup>, Reduces Neutrophil/Lymphocyte Ratio in the Elderly: A Double-Blind, Placebo-Controlled Clinical Trial","year":2021,"lang":"en","type":"article","venue":"Journal of Nutritional Science and Vitaminology","topic":"Curcumin's Biomedical Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Debiopharm Group (Canada)","funders":"","keywords":"Medicine; Placebo; Lymphocyte; White blood cell; Internal medicine; Curcumin; Neutrophil to lymphocyte ratio; Absolute neutrophil count; Gastroenterology; Immunology; Clinical trial; Placebo-controlled study; Pharmacology; Double blind; Pathology; Toxicity; Neutropenia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002714537,0.0002364119,0.0005429132,0.0003034025,0.000392142,0.000160668,0.0007120908,0.0003406231,0.00003886741],"category_scores_gemma":[0.00115741,0.0001739913,0.0002113102,0.001020021,0.001011534,0.00008877818,0.0001752284,0.0003470426,0.00001155904],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009506987,"about_ca_system_score_gemma":0.002371612,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007466084,"about_ca_topic_score_gemma":0.00003195548,"domain_scores_codex":[0.9965061,0.0002978312,0.0013549,0.00058444,0.0007686007,0.0004881362],"domain_scores_gemma":[0.9973253,0.0004064394,0.0005690665,0.0003261283,0.001139892,0.0002331944],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.1208701,0.003317733,0.0007826049,0.00004267281,0.0002844422,0.0001948613,0.0003196975,0.000104621,0.8285611,0.01487757,0.01572338,0.01492121],"study_design_scores_gemma":[0.5988634,0.007003453,0.0076799,0.0001480221,0.0003013708,0.00324411,0.0007600104,0.00113332,0.04877695,0.006524971,0.3246147,0.0009497624],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829979,0.002052841,0.0008534303,0.01271461,0.0003708772,0.0007264247,0.0000220675,0.000007142306,0.0002546908],"genre_scores_gemma":[0.993827,0.001429842,0.002071848,0.0009102877,0.001329945,0.0001243106,0.0000873028,0.00001268257,0.0002067417],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7797842,"threshold_uncertainty_score":0.7095159,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05601092681220768,"score_gpt":0.3451332955919999,"score_spread":0.2891223687797922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}