{"id":"W3196428188","doi":"10.1101/2020.12.20.423651","title":"Centimeter-scale quorum sensing dictates collective survival of differentiating embryonic stem cells","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institute for Advanced Research","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Canadian Institute for Advanced Research","keywords":"Embryonic stem cell; Quorum sensing; Biology; Centimeter; Cell; Cell biology; Population; Stem cell; Physics; Biofilm; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000207347,0.0001968501,0.0002081108,0.0001093441,0.0001984357,0.0003654597,0.0001575959,0.0001880612,0.0007162341],"category_scores_gemma":[0.0002639005,0.0002158613,0.0001694658,0.00008930462,0.0002913542,0.0002318555,0.0003984734,0.0004711222,0.0002555248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005375079,"about_ca_system_score_gemma":0.0002450095,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000903755,"about_ca_topic_score_gemma":0.001312484,"domain_scores_codex":[0.9998975,0.00001324922,0.000007984921,0.00002252146,0.000043816,0.00001489377],"domain_scores_gemma":[0.9997987,0.00006573831,0.00006061667,0.00002194717,0.00001858889,0.00003431292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000190564,0.000006026305,0.00127556,0.00001832832,0.000002940103,0.00003407613,0.00002321958,0.00194202,0.9952434,0.0006444519,0.00003614418,0.0007546213],"study_design_scores_gemma":[0.00001591827,0.0001031849,0.01880103,0.0000111257,0.00001308615,0.0001112265,0.000167507,0.0413556,0.9355305,0.002105884,0.001764221,0.00002076823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865465,0.0002166294,0.01171276,0.0001386517,0.00001037368,0.000008798787,0.0001823752,0.00004490389,0.001138951],"genre_scores_gemma":[0.9961919,0.0001347993,0.003067508,0.00002413073,0.000003339331,0.00001169512,0.00009265005,0.00001020866,0.0004637117],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000903755,"threshold_uncertainty_score":0.003899932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01457240037373691,"score_gpt":0.2077536509079543,"score_spread":0.1931812505342173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}