{"id":"W3196544009","doi":"10.4236/pp.2021.128014","title":"Development of a Method for Identification and Quantification of Sulfadiazine and Pyrimethamine in Serum of Congenital Toxoplasmosis Pediatric Patients","year":2021,"lang":"en","type":"article","venue":"Pharmacology &amp Pharmacy","topic":"Toxoplasma gondii Research Studies","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Comisión de Investigaciones Científicas; Agencia Nacional de Promoción Científica y Tecnológica; Consejo Nacional de Investigaciones Científicas y Técnicas","keywords":"Sulfadiazine; Pyrimethamine; Toxoplasmosis; Chromatography; Medicine; Congenital toxoplasmosis; Toxoplasma gondii; Therapeutic drug monitoring; Atovaquone; Pharmacology; Chemistry; Drug; Antibiotics; Malaria; Virology; Immunology; Chloroquine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001249386,0.0007882328,0.0005004348,0.001347036,0.0003430633,0.0004764668,0.0005780623,0.00118414,0.0006063241],"category_scores_gemma":[0.001379312,0.0005148216,0.0004371642,0.0005169589,0.0004231732,0.0002709055,0.000490515,0.0007791908,0.0004644034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003918835,"about_ca_system_score_gemma":0.0009948423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009475428,"about_ca_topic_score_gemma":0.001949464,"domain_scores_codex":[0.9978517,0.0006259448,0.0001525133,0.0003601687,0.000912617,0.00009704066],"domain_scores_gemma":[0.999337,0.000174926,0.0001577229,0.00004355067,0.0002335754,0.00005315684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002994243,0.000247602,0.01158816,0.0003446375,0.00008985837,0.0002220252,0.0001818346,0.0004147503,0.9527067,0.0001842129,0.0003459006,0.03337497],"study_design_scores_gemma":[0.0001012452,0.002473106,0.03319351,0.0001186156,0.0001318444,0.004054703,0.0001535807,0.009300312,0.9426923,0.0002089695,0.007506306,0.00006539678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.7433606,0.01855943,0.2265204,0.0009180388,0.0004966919,0.001376055,0.001715569,0.001726904,0.005326245],"genre_scores_gemma":[0.739678,0.004537353,0.2494093,0.0007390641,0.0001009384,0.0009170041,0.001261854,0.0000525256,0.003303903],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001347036,"threshold_uncertainty_score":0.006607473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04662671394815708,"score_gpt":0.3770593017236193,"score_spread":0.3304325877754622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}