{"id":"W3196590882","doi":"10.1530/rep-21-0270","title":"Regulation of dual specificity phosphatases by fibroblast growth factor signaling pathways in bovine granulosa cells","year":2021,"lang":"en","type":"article","venue":"Reproduction","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Ottawa Fertility Centre; Cegep de Saint Hyacinthe","funders":"","keywords":"Cell biology; Phosphatase; Kinase; Biology; DUSP6; Protein kinase C; MAPK/ERK pathway; Signal transduction; Protein kinase A; Fibroblast growth factor; Molecular biology; Chemistry; Protein phosphatase 2; Biochemistry; Phosphorylation; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001769414,0.0001387838,0.0001635109,0.00003765788,0.00004094545,0.00001537105,0.00006443601,0.00009625326,0.00006406533],"category_scores_gemma":[0.0003045406,0.000153428,0.00006082016,0.000213615,0.00005413945,0.00001614503,0.00006967747,0.00007245271,0.000004531486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002656048,"about_ca_system_score_gemma":0.00005932536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007850993,"about_ca_topic_score_gemma":0.00001409028,"domain_scores_codex":[0.9986511,0.00008042826,0.0003204155,0.0006152765,0.0001654972,0.0001672634],"domain_scores_gemma":[0.9991406,0.000009344584,0.0001605395,0.0004767801,0.0001749366,0.00003785247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001181565,0.0001346775,0.0006016521,0.00006337288,0.00001278381,0.000003396361,0.0000239827,0.0001584111,0.9946435,0.0001672192,0.002739431,0.00133343],"study_design_scores_gemma":[0.000311859,0.0001502653,0.003432085,0.00004323852,0.000007436651,0.00001297884,0.00003502204,0.00001250977,0.9939312,0.0001938829,0.00171843,0.0001511184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898143,0.008061983,0.00108902,0.0001029712,0.000186026,0.0002015639,0.0004984853,0.0000171185,0.00002850918],"genre_scores_gemma":[0.996348,0.0002736496,0.001056938,0.00001402174,0.0002941577,0.00001034206,0.001865583,0.00001863733,0.0001186549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007788333,"threshold_uncertainty_score":0.6256613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01153772021286721,"score_gpt":0.2147643442244611,"score_spread":0.2032266240115939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}