{"id":"W3196656285","doi":"10.1038/s41393-021-00699-1","title":"Clinical trials and tribulations: lessons from spinal cord injury studies registered on ClinicalTrials.gov","year":2021,"lang":"en","type":"article","venue":"Spinal Cord","topic":"Spinal Cord Injury Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"International Collaboration On Repair Discoveries; iCo Therapeutics (Canada); University of British Columbia","funders":"","keywords":"Medicine; Clinical trial; Spinal cord injury; Randomized controlled trial; Etiology; Physical therapy; Spinal cord; Surgery; Internal medicine; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.009850259,0.0004560386,0.00282067,0.0002550645,0.0003098688,0.0001253309,0.0002861085,0.000419329,0.0003733052],"category_scores_gemma":[0.06695315,0.0003784092,0.0006808178,0.0006789897,0.0006577264,0.0001431111,0.0004057398,0.001445387,0.0002754395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002458465,"about_ca_system_score_gemma":0.0008826784,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009346438,"about_ca_topic_score_gemma":0.00005776186,"domain_scores_codex":[0.9910103,0.002828372,0.003033168,0.001358555,0.001131063,0.0006385085],"domain_scores_gemma":[0.9918494,0.003891671,0.0009000124,0.001489361,0.001186575,0.0006829973],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.4144112,0.0009283294,0.01334464,0.0002217669,0.001150081,0.0007364996,0.000009273871,1.005518e-7,0.003701492,0.002305655,0.01335703,0.5498339],"study_design_scores_gemma":[0.02085208,0.3116858,0.4852467,0.005663679,0.002761466,0.0002182736,0.001435008,0.00007706705,0.004964705,0.01250562,0.1533114,0.001278271],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9618563,0.01122406,0.0001882851,0.02261367,0.001762614,0.001313803,0.0001977889,0.0001349481,0.0007085443],"genre_scores_gemma":[0.9764152,0.009505061,0.004957928,0.002967884,0.003535688,0.0001177912,0.0001249757,0.00007203654,0.002303451],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5485556,"threshold_uncertainty_score":0.9998668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.7229663642545334,"score_gpt":0.656380952332715,"score_spread":0.06658541192181844,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}