{"id":"W3196783006","doi":"10.1136/gutjnl-2021-iddf.80","title":"IDDF2021-ABS-0078 Switching from tenofovir disoproxil fumarate (TDF) and/or other oral antivirals (OAVS) to tenofovir alafenamide (TAF) in virally suppressed chronic hepatitis B (CHB) patients with moderate or severe renal impairment, or with end-stage renal disease (ESRD)","year":2021,"lang":"en","type":"article","venue":"","topic":"Hepatitis C virus research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Liver Centre; University of Calgary; Université de Montréal; Toronto General Hospital; University Health Network","funders":"","keywords":"Medicine; Tenofovir alafenamide; Internal medicine; Gastroenterology; Tenofovir; Hepatitis B; Entecavir; Creatinine; Viral load; Adverse effect; HBeAg; Urology; Chronic hepatitis; HBsAg; Hepatitis B virus; Lamivudine; Immunology; Human immunodeficiency virus (HIV); Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006033671,0.0002726156,0.0004059093,0.0001076359,0.0002748443,0.0004125058,0.0002654479,0.0005758727,0.01777907],"category_scores_gemma":[0.0002834696,0.0001172373,0.0002934881,0.0001381435,0.0002991696,0.0001504844,0.0002217709,0.0007215009,0.003838671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003384941,"about_ca_system_score_gemma":0.0008627035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00118389,"about_ca_topic_score_gemma":0.00191376,"domain_scores_codex":[0.9997836,0.00007753553,0.00002709442,0.00002584677,0.00002755681,0.00005849419],"domain_scores_gemma":[0.9997631,0.00003597619,0.0000367895,0.00003164257,0.0000224014,0.0001101147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.185725,0.02803156,0.0627668,0.001098626,0.0003658732,0.002225416,0.0002576998,0.0009716811,0.1835417,0.001825119,0.06012047,0.4730701],"study_design_scores_gemma":[0.1008971,0.2885823,0.2625694,0.0005170074,0.0005250276,0.007339165,0.0004727473,0.004747639,0.05551615,0.001076968,0.2776687,0.00008776037],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9395634,0.002179449,0.001588601,0.00128193,0.0007192592,0.004019065,0.008088191,0.0003370679,0.04222303],"genre_scores_gemma":[0.9532537,0.001244574,0.003922302,0.002809688,0.0004986762,0.002397015,0.009996864,0.00008154559,0.02579561],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.01777907,"threshold_uncertainty_score":0.05947697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02160904017592897,"score_gpt":0.2881003531402515,"score_spread":0.2664913129643225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}