{"id":"W3196810602","doi":"10.1093/jnen/nlab090","title":"Nuclear IMPDH Filaments in Human Gliomas","year":2021,"lang":"en","type":"article","venue":"Journal of Neuropathology & Experimental Neurology","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Ottawa Hospital; St. Michael's Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health; Ottawa Hospital Research Institute; Howard Hughes Medical Institute","keywords":"Cancer research; Glioma; Chemistry; Computational biology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009292432,0.0001340812,0.00008745561,0.0006828412,0.0001479647,0.0001718251,0.00009014335,0.0001741344,0.001516002],"category_scores_gemma":[0.0001701765,0.0001042368,0.00008225561,0.0003067899,0.0001570481,0.0001199688,0.0001787999,0.00009711781,0.0003480416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000152713,"about_ca_system_score_gemma":0.00007933041,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001157611,"about_ca_topic_score_gemma":0.001364334,"domain_scores_codex":[0.9999367,0.000008784671,0.000006273578,0.00001488568,0.00002170817,0.00001160199],"domain_scores_gemma":[0.9999052,0.000012103,0.0000324478,0.000009819992,0.00001997711,0.00002042932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008553199,0.00003506193,0.03522752,0.0002028189,0.00002715607,0.002921687,0.0002506976,0.0001002478,0.9444233,0.000280915,0.0002486024,0.01542673],"study_design_scores_gemma":[0.00004570003,0.001009032,0.6220891,0.00007942652,0.0001036598,0.03750611,0.0007301733,0.001192768,0.3192282,0.0005565038,0.01742955,0.00002981129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879364,0.005787381,0.001942366,0.00005437079,0.00001624708,0.00002149776,0.0003440591,0.0000810852,0.003816469],"genre_scores_gemma":[0.9965752,0.001271243,0.0008615607,0.0000156815,0.000006551927,0.00001011296,0.0002991983,0.000006588117,0.0009538541],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001516002,"threshold_uncertainty_score":0.00507158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01199039547581251,"score_gpt":0.2993253982954498,"score_spread":0.2873350028196373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}