{"id":"W3196819503","doi":"10.1139/bcb-2021-0093","title":"RNF38 inhibits osteosarcoma cell proliferation by binding to CRY1","year":2021,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Beetle Biology and Toxicology Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"PI3K/AKT/mTOR pathway; Protein kinase B; Osteosarcoma; Gene knockdown; Cell growth; Cancer research; Biology; Immunoprecipitation; Signal transduction; Blot; Cell biology; Molecular biology; Chemistry; Cell culture; Gene; Biochemistry; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001957624,0.0005496487,0.0003590565,0.0003034729,0.0002280513,0.0001041438,0.0002317728,0.0002689389,0.002293327],"category_scores_gemma":[0.0000979574,0.0001525803,0.0003748612,0.000193977,0.000184196,0.0001409097,0.0001721457,0.0005328062,0.000385561],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004036757,"about_ca_system_score_gemma":0.0002924688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009983934,"about_ca_topic_score_gemma":0.00153491,"domain_scores_codex":[0.9997885,0.000032813,0.00001655558,0.00003489429,0.00006073491,0.00006649769],"domain_scores_gemma":[0.9999459,0.000008320838,0.00001560476,0.000005808881,0.000007614963,0.00001672044],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001356934,0.00007165553,0.0001340526,0.0001038862,0.00000681478,0.00003620195,0.00001306558,0.00009135858,0.9974455,0.00004556927,0.0001742622,0.001742049],"study_design_scores_gemma":[0.00006465755,0.0007271623,0.004366385,0.00001478638,0.00001806919,0.0002432963,0.00003021691,0.001427656,0.988042,0.00004999656,0.005009397,0.000006407333],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881484,0.00586884,0.002636495,0.0002664568,0.00008654709,0.00005698107,0.0006839473,0.0002746922,0.001977583],"genre_scores_gemma":[0.9877465,0.002754444,0.003969103,0.00009292088,0.00002350537,0.0001476239,0.001308211,0.00002918033,0.003928429],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002293327,"threshold_uncertainty_score":0.007671893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0069629996304831,"score_gpt":0.2291192032465008,"score_spread":0.2221562036160177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}