{"id":"W3196932605","doi":"10.1007/s10719-021-10020-0","title":"Cross-reactivity of Haemophilus influenzae type a and b polysaccharides: molecular modeling and conjugate immunogenicity studies","year":2021,"lang":"en","type":"article","venue":"Glycoconjugate Journal","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"National Research Council Canada","funders":"University of Capetown","keywords":"Serotype; Immunogenicity; Haemophilus influenzae; Microbiology; Conjugate vaccine; Polysaccharide; Virology; Biology; Conjugate; Antibody; Immunology; Antibiotics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003731317,0.0001914155,0.000467073,0.00009099244,0.0003507602,0.00008566401,0.00007518174,0.0001685674,0.0001264622],"category_scores_gemma":[0.0003811561,0.0001648423,0.00007876878,0.0001569691,0.0002184119,0.0002822498,0.0001885252,0.000391418,0.000008766548],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002543501,"about_ca_system_score_gemma":0.0001227999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001505191,"about_ca_topic_score_gemma":0.00002157787,"domain_scores_codex":[0.9988444,0.0001697082,0.0004615381,0.0002359551,0.00002558112,0.0002627982],"domain_scores_gemma":[0.9987592,0.00009656221,0.000213843,0.000181421,0.0007065925,0.0000424231],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003024392,0.00005543838,0.00419979,0.00003482959,0.0006250866,0.00002513758,0.0003279265,0.00008516803,0.9918972,0.0002391454,0.00002053785,0.002187259],"study_design_scores_gemma":[0.004588322,0.0004757863,0.00778271,0.0002285281,0.0003400466,0.008915655,0.0008158901,0.0001909467,0.9702282,0.003049688,0.002907154,0.0004771023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9669383,0.0318437,0.0001021405,0.0001715325,0.0007691579,0.00008409052,0.00001895469,0.00002034101,0.00005173678],"genre_scores_gemma":[0.9949135,0.004718242,0.0001062841,0.00008721869,0.00004974945,0.000002817439,0.000005757979,0.00001456077,0.0001018495],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02797517,"threshold_uncertainty_score":0.6722072,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03149834264490771,"score_gpt":0.3096206796565388,"score_spread":0.2781223370116311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}