{"id":"W3196997336","doi":"10.1016/j.celrep.2021.109647","title":"Transcriptional control of brain tumor stem cells by a carbohydrate binding protein","year":2021,"lang":"en","type":"article","venue":"Cell Reports","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill Genome Centre; McGill University; Jewish General Hospital","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Cancer Research Society; Harvard Medical School","keywords":"Biology; Transcription factor; Carcinogenesis; Downregulation and upregulation; Stem cell; Transcriptional regulation; Regulation of gene expression; Cancer research; Gene; Glioblastoma; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009022565,0.0001490464,0.0001003713,0.0001411041,0.00009149819,0.0002758755,0.00008642338,0.0001225551,0.0007220443],"category_scores_gemma":[0.0000534774,0.00004661422,0.0001248546,0.00009547416,0.0002069179,0.00009868101,0.0001668652,0.0003875417,0.0002511478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003542183,"about_ca_system_score_gemma":0.0002098895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004555486,"about_ca_topic_score_gemma":0.001087669,"domain_scores_codex":[0.9999132,0.0000147253,0.000005604445,0.00001495749,0.00003107972,0.00002041045],"domain_scores_gemma":[0.9999565,0.000006156649,0.00001418264,0.000004854946,0.000005906816,0.00001238004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002503151,0.000007416906,0.0002011804,0.00001272698,0.000001661498,0.0000168628,0.000009484377,0.00006283541,0.9973295,0.0002573494,0.00004001428,0.002035987],"study_design_scores_gemma":[0.00000489425,0.00009283055,0.00399826,0.000004571943,0.000006764166,0.000112807,0.00005097912,0.001030722,0.9901761,0.0001459519,0.004374204,0.000001992477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882305,0.002115317,0.006433874,0.0002625878,0.00002562813,0.00002005465,0.0003150753,0.00009855479,0.002498336],"genre_scores_gemma":[0.994938,0.0007671727,0.002027696,0.00005619581,0.000006096378,0.00001662895,0.0002881791,0.00001368327,0.001886265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007220443,"threshold_uncertainty_score":0.002570033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006931418402363943,"score_gpt":0.1968021834262969,"score_spread":0.189870765023933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}