{"id":"W3196997336","doi":"10.1016/j.celrep.2021.109647","title":"Transcriptional control of brain tumor stem cells by a carbohydrate binding protein","year":2021,"lang":"en","type":"article","venue":"Cell Reports","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill Genome Centre; McGill University; Jewish General Hospital","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Cancer Research Society; Harvard Medical School","keywords":"Biology; Transcription factor; Carcinogenesis; Downregulation and upregulation; Stem cell; Transcriptional regulation; Regulation of gene expression; Cancer research; Gene; Glioblastoma; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002159749,0.0001303155,0.0003014966,0.00004120562,0.00007059901,0.000006436785,0.00006065644,0.0001487914,0.0006630554],"category_scores_gemma":[0.00001189896,0.0001216359,0.0001178916,0.0001096293,0.0001034539,0.00002571806,0.00001688271,0.0001736971,0.00002667691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002834724,"about_ca_system_score_gemma":0.0001971769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004408554,"about_ca_topic_score_gemma":0.00001232054,"domain_scores_codex":[0.9987838,0.0001623872,0.000418333,0.0003348348,0.00003366566,0.0002669638],"domain_scores_gemma":[0.9993567,0.00004200379,0.0002583271,0.0002272786,0.00009216222,0.0000235669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003943636,0.0001067862,0.0007437491,0.00003758868,0.0000660675,0.0002306949,0.00006963855,0.000003602132,0.9953569,0.00006059117,0.002989121,0.0002958911],"study_design_scores_gemma":[0.0006304736,0.00009758816,0.00009290215,0.0000203433,0.00002525603,0.0002878577,0.00009322057,0.00000104253,0.9200881,0.00003271809,0.07851703,0.000113505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918675,0.004983362,0.0002771364,0.0001683313,0.0008028918,0.0002399771,0.0000726592,0.00002714632,0.001561002],"genre_scores_gemma":[0.9780678,0.00001086941,0.00001772384,0.0001362211,0.00001710677,0.00004244253,0.00007700905,0.00001299026,0.02161783],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07552791,"threshold_uncertainty_score":0.7259992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006931418402363943,"score_gpt":0.1968021834262969,"score_spread":0.189870765023933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}