{"id":"W3197000240","doi":"10.1016/s2152-2650(21)01747-x","title":"CLL-045: Long-Term Follow-up, Up to 7 Years, in the RESONATE-2 Study of First-Line Ibrutinib Treatment for Chronic Lymphocytic Leukemia (CLL)","year":2021,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Ibrutinib; Chlorambucil; Medicine; Chronic lymphocytic leukemia; Internal medicine; IGHV@; Gastroenterology; Oncology; Leukemia; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00357551,0.001003667,0.001682034,0.0005184062,0.0007671461,0.001947876,0.0009490488,0.001761321,0.00191631],"category_scores_gemma":[0.002492649,0.0005733805,0.001941387,0.0006836327,0.0006798134,0.00172131,0.001093368,0.001915212,0.0006310482],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001092774,"about_ca_system_score_gemma":0.0009382524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002607672,"about_ca_topic_score_gemma":0.004527791,"domain_scores_codex":[0.998632,0.0005586231,0.00008423578,0.0002687313,0.0001406219,0.000315741],"domain_scores_gemma":[0.9982413,0.0002684979,0.0005336139,0.0002129006,0.0001752559,0.0005684464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.4402865,0.004163024,0.4849946,0.0006216049,0.008379264,0.0006202639,0.0006241688,0.001212606,0.005158793,0.0002581996,0.00353529,0.0501457],"study_design_scores_gemma":[0.02900215,0.07128149,0.8790012,0.0002450251,0.00755841,0.0008153294,0.0006261765,0.001230814,0.001566685,0.0003453802,0.008173415,0.0001539852],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924988,0.004152685,0.0001941275,0.000183666,0.00007979317,0.00009687033,0.001688448,0.0000219231,0.001083658],"genre_scores_gemma":[0.9921827,0.0007047483,0.0001972588,0.000367287,0.0001132066,0.0001571933,0.005043401,0.000009696622,0.001224479],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00357551,"threshold_uncertainty_score":0.01890928,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09057944067365786,"score_gpt":0.3987449423069644,"score_spread":0.3081655016333066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}