{"id":"W3197018455","doi":"10.1128/msystems.00925-21","title":"Retooling Microbiome Engineering for a Sustainable Future","year":2021,"lang":"en","type":"article","venue":"mSystems","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Microbiome; Bioremediation; Function (biology); Intestinal Microbiome; Biochemical engineering; Gut microbiome; Biotechnology; Engineering; Biology; Bioinformatics; Evolutionary biology; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002851664,0.0006902497,0.0005110945,0.0006088179,0.001060285,0.002861878,0.001197612,0.002445291,0.003417336],"category_scores_gemma":[0.003066109,0.0003107213,0.00089163,0.0003071993,0.002891003,0.005132577,0.003676999,0.005443683,0.001423663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001347972,"about_ca_system_score_gemma":0.002329359,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009161701,"about_ca_topic_score_gemma":0.001922092,"domain_scores_codex":[0.9990001,0.0002430643,0.00005145638,0.0001680253,0.0004031391,0.000134256],"domain_scores_gemma":[0.9988983,0.0005096693,0.00009676704,0.0001219559,0.000196646,0.0001766815],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001845274,0.00009455183,0.001019561,0.002358361,0.00014446,0.0006140023,0.001613718,0.009588477,0.1146601,0.425186,0.1394661,0.3050702],"study_design_scores_gemma":[0.00001244067,0.00005981011,0.0002656685,0.0003768676,0.00003668084,0.0001773794,0.0003907374,0.004035906,0.02004478,0.149729,0.8248233,0.00004733517],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.0283964,0.2167995,0.2837786,0.3600852,0.05571306,0.0001750435,0.0004961863,0.003484255,0.05107178],"genre_scores_gemma":[0.3379139,0.2645536,0.2041733,0.1056413,0.0200951,0.0004858577,0.0008998029,0.002301323,0.06393573],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003417336,"threshold_uncertainty_score":0.01508123,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003049498860401584,"score_gpt":0.1908046026542229,"score_spread":0.1877551037938213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}